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Now showing items 9872-9891 of 10629
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TLR5 participates in the TLR4 receptor complex and promotes MyD88- dependent signaling in environmental lung injury
(2020-01-28)Lung disease causes significant morbidity and mortality, and is exacerbated by environmental injury, for example through lipopolysaccharide (LPS) or ozone (O3). Toll-like receptors (TLRs) orchestrate immune responses to ... -
TMEFF2 is an epigenetic modulator that promotes androgen independent growth in castration-resistant prostate cancer cells
(East Carolina University, 2014)While the ability to detect PCa has improved significantly due to PSA screenings, the survival rate for men diagnosed with PCa has remained stagnant, and the disease remains the second leading cause of cancer related deaths ... -
TNM cancer staging: can it help develop a novel staging system for type 2 diabetes?
(2018-11-28)Type 2 diabetes (DM2) constitutes 90%–95% of the diabetes cases and is increasing at an alarming rate in the world. The Centers for Disease Control and Prevention (CDC) estimates that more than 29 million people in the ... -
TNM cancer staging: can it help develop a novel staging system for type 2 diabetes?
(2018-11-28)Abstract: Type 2 diabetes (DM2) constitutes 90%–95% of the diabetes cases and is increasing at an alarming rate in the world. The Centers for Disease Control and Prevention (CDC) esti- mates that more than 29 million people ... -
TO BE OR NOT TO BE A (ROLE) MODEL IN A GLASS (CEILING) MENAGERIE
(2015-04-28)This paper explores how famous female characters express societal views and expectations for actual females and presents ways new works can provide expanded options, liberating performers and audiences from restrictive ... -
TO BE, RATHER THAN TO SEEM: STUDENT PERCEPTIONS OF THE IMPORTANCE OF HISTORY IN THE 9-12 CURRICULUM
(East Carolina University, 2016-12-07)There has been a recent emphasis on Science Technology Engineering Mathematics (STEM) education, an area that seems to be growing even when budget cuts hit. The present study investigates whether high school students ... -
To Love Me Too
(East Carolina University, 2021-05-10)My flash non-fiction practice is influenced by Randon Billings Noble and Jennifer Marie Brissett, while my imagery and interest in black diaspora is rooted in slave narratives, and African and African American literature. ... -
"To Understand Me, You'll Have to Swallow a World:" Understanding Rhetorical Confusion in Transnational Literature
(East Carolina University, 2019-04-23)This thesis aims to define and explore the concept of rhetorical confusion as a pattern that exists within transnational literature. Specifically, rhetorical confusion is defined as a trend within transnational texts in ... -
Together We Can: Increase Couple Functioning for Low-SES Families
(East Carolina University, 2018-05-02)This study was conducted to understand how parenting efficacy and the co-parenting relationship are influenced by the adapted Together We Can relationship program. Researchers were interested in determining how socioeconomic ... -
Tolerogenic vaccines for multiple sclerosis
(2013-01-28)Tolerogenic vaccines represent a new class of vaccine designed to re-establish immunological tolerance, restore immune homeostasis, and thereby reverse autoimmune disease. Tolerogenic vaccines induce long-term, antigen-specific, ... -
Tolerogenic vaccines for Multiple Sclerosis
(2013-05)Tolerogenic vaccines represent a new class of vaccine designed to re-establish immunological tolerance, restore immune homeostasis, and thereby reverse autoimmune disease. Tolerogenic vaccines induce long-term, antigen-specific, ... -
Tomol's and the "carrying of many people": Indigenous control of the sea in the Santa Barbara Channel
(East Carolina University, 2018-04-24)The Indigenous Chumash people of the California coast relied heavily upon the wealth of maritime resources that the Santa Barbara Channel provided. In order to access these vast resources, the use of advanced sewn vessels, ... -
"The Tonic of Wildness" : Thoreau's Critique of Industrial Capitalism
(East Carolina University, 2015)This thesis is a critical intervention in contemporary Thoreau scholarship. It argues against Ashton Nichols's application of his concept of "urbanature" to the writings and philosophy of Henry David Thoreau. Thoreau's ...