Browsing by Title
Now showing items 2141-2160 of 10618
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CRISPR/Cas9 knockout of HAS2 in rat chondrosarcoma chondrocytes demonstrates the requirement of hyaluronan for aggrecan retention
(East Carolina University, 2016-12-15)Hyaluronan (HA) plays an essential role in cartilage where it functions to retain aggrecan. Previous studies suggested that aggrecan is anchored indirectly to the plasma membrane of chondrocytes via its binding to ... -
CRISPR/CAS9 SYSTEMS FOR PLANT GENOME EDITING
(East Carolina University, 2016-04-28)The increasing burden of the world population on agriculture requires the development of more robust crops. Dissecting the basic biology that underlies plant susceptibility to pathogens and drives crop loss will inform ... -
A CRISPR/Cas9 Toolbox for Multiplexed Plant Genome Editing and Transcriptional Regulation
(2015)The relative ease, speed and biological scope of CRISPR/Cas9-based reagents for genomic manipulations are revolutionizing virtually all areas of molecular biosciences, including functional genomics, genetics, applied ... -
Critical Literacy in Fairytales: Through the Eyes of a Preschooler
(East Carolina University, 2023-04-26)Critical literacy theory says that students can make connections between a text and the meaning of its words, thereby, connecting it to societal ideas around them. Critical literacy in the classroom has often been tied ... -
A Critical Look at Campus Climate After Institutional Changes
(East Carolina University, 2015)This study examines the impact of institutional changes on campus climate. Conditions continue to be problematic for LGBTQ students, faculty and staff on college and university campuses, so many institutions are taking ... -
CRNA DNP Project: ECG Lead Placement in the Perioperative Setting: A Quality Improvement Project
(2023-12-06)Proper electrocardiogram (ECG) placement is an important aspect of reliable cardiac monitoring during the perioperative period. Inaccurate and/or inconsistent ECG lead placement has the potential to lead to incorrect, ... -
Crop rotational diversity increases disease suppressive capacity of soil microbiomes
(2018-05-15)Microbiomes can aid in the protection of hosts from infection and disease, but the mechanisms underpinning these functions in complex environmental systems remain unresolved. Soils contain microbiomes that influence plant ... -
Cross-cultural Online Learning in Technical Communication Courses: Aiming for Intercultural Competence
(East Carolina University, 2017-05-03)Teaching online in cross-cultural contexts is still a fairly new phenomenon. My research explores the impact of culture on the learners and instructors in four technical communication online courses. My study uses a ... -
Cross-Generational Valuing Among Peer Academic Librarians
(2015)This study addresses a gap in the research concerning generational roles in the academic library workforce, particularly with regard to Millennials. -
Cross-Generational Valuing Among Peer Academic Librarians
(2015)This study investigated the skills, knowledge, abilities or dispositions that are most valued and respected by academic librarians, and determined how these qualities might, or might not, be associated with generational ... -
Cross-generational Valuing Among Peer Academic Librarians: A Preliminary Report Following Up with Millennials
(2015-03-26)Paper presents a preliminary analysis of survey research designed to elicit information about Millennial academic librarians, their most valued colleagues at work, and reasons why they value these colleagues, and compares ... -
Cross-National Variation in Aggregate Levels of Life Satisfaction of Gay Men
(East Carolina University, 2021-01-07)This project examined the cross-national variation in aggregate levels of life satisfaction of gay men. Using data from the Gay Happiness Index, the World Values Survey, the European Values Study, the International Lesbian, ... -
Crossing the Line : A Look at the Symbols of the Ritual throughout Time
(East Carolina University, 2014)During the Age of Sail, sailors often marked their experience by the crossing of the equator or another Tropic line. This crossing indicated that the sailor had moved from the rank of inexperienced pollywog to the new ... -
Crowdsourcing Digitization: Harnessing Workflows to Increase Output
(East Carolina University, 2008-10-16)Are the highly selective models of digital content creation satisfying user demands for increasing access to our vast collection holdings? In this era of decreasing library budgets and increasing responsibilities, is such ... -
Crucial Factors for the Recovery and Conservation of an Archaeological Ship
(East Carolina University, 2012)What factors determine the successful recovery and concentration of a full archaeological ship? While an article by G.D. van der Heide provides guidelines for recovery, he offers no analysis to explain why his issues are ... -
Cruising for Plants and Progress: Marian and David Fairchild and the Allison V. Armour Expeditions, 1925-1933
(East Carolina University, 2019-07-23)This thesis examines the Allison V. Armour Expeditions that took place between 1925 and 1933 aboard research vessel Utowana. Led by American botanist David G. Fairchild and sponsored by philanthropist Allison V. Armour, ... -
Cryo-electron tomography of periplasmic flagella in Borrelia burgdorferi reveals a distinct cytoplasmic ATPase complex.
(2018-11-09)Periplasmic flagella are essential for the distinct morphology and motility of spirochetes. A flagella-specific type III secretion system (fT3SS) composed of a membrane-bound export apparatus and a cytosolic ATPase complex ... -
Cryptic Seed Heteromorphism in Packera tomentosa (Asteraceae) : Differences in Seed Mass Characteristics and Germination
(East Carolina University, 2012)Germination requirements of seeds can dictate when and where plant offspring establish. Microsites available for germination vary spatially and temporally in factors such as temperature and moisture; thus, the production ...