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Now showing items 430-449 of 10619
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An Algorithm for Using Hydroxyurea in Sickle Cell Disease
(2021-07-26)Sickle Cell Disease (SCD) is an inherited blood disorder that affects many African Americans globally. This disease is characterized by acute complications from chronic anemia, episodes of painful acute on chronic ... -
Alienation and Ethnic Identities in "Growing Up Ethnic in America," "Borderlands/La Frontera," and "The Day Nina Simone Stopped Singing"
(East Carolina University, 2015)This thesis examines the concept of alienation during adolescence as an influential factor in ethnic identity development. The negative effects of alienation are frequently explored, but I argue experiences concerning ... -
AlienG2 - An Automated Analysis Tool for Genome-scale Prediction of Horizontal Gene Transfer
(East Carolina University, 2013)This thesis will present a method for predicting Horizontal Gene Transfer (HGT) events through the creation of a web-based application called AlienG2. HGT is the process of genetic exchange between distantly related ... -
Alkaloid defenses of co-mimics in a putative Müllerian mimetic radiation
(2014)Background Polytypism in aposematic species is unlikely according to theory, but commonly seen in nature. Ranitomeya imitator is a poison frog species exhibiting polytypic mimicry of three congeneric model species (R. ... -
All Hands on Deck Mentoring Program
(East Carolina University, 2021-04-23)At the beginning of our freshman year, we were assigned the project of addressing a “wicked” problem, or a problem that is unsolvable. Being tasked with this, we decided to address an issue that directly affected us, and ... -
All Hands on Deck Mentorship Program
(East Carolina University, 2022-05-09)At the beginning of our freshman year, we were assigned the project of addressing a “wicked” problem, or a problem that is unsolvable. Being tasked with this, we decided to address an issue that directly affected us, and ... -
ALL IS NOT FAIR IN THE APPRAISALS OF PERFORMANCE: APPRAISALS, JUSTICE, AND WORK OUTCOMES
(East Carolina University, 2019-04-12)This study examined the moderating effect of core self-evaluation (CSE) on the relationship between perceptions of procedural performance appraisal justice (PAJ) and the components of engagement (vigor, dedication, and ... -
All's well that begins Wells: Celebrating 60 years of Animal Behaviour and 36 years of research on anuran social behaviour
(2012-12-04)The scientific study of frogs and toads as important systems in behavioural ecology traces its roots to an influential review published in this journal 36 years ago (Wells 1977a, ‘The social behaviour of anuran amphibians’, ... -
Allen Oldfather Whipple:The Father of Modern Pancreatic Surgery.
(2008-04-14)Laupus Library History Collections & the Department of Bioethics & Interdisciplinary Studies sponsor the History of Medicine Presentations as an educational service for the East Carolina University community. The Library ... -
Allopurinol improves myocardial reperfusion injury in a xanthine oxidase-free model
(East Carolina University, 1995-07)The ability of allopurinol to protect against reperfusion injury in the heart has usually been attributed to its xanthine oxidase (XO)- inhibiting properties. Human myocardium how- ever, has exhibited low levels of XO ... -
Alone Together? Fighting Student Isolation in Online Art Education
(2022-07)The COVID-19 pandemic required most K-16 educators to transition to the realm of online education. Across the nation, a plethora of insights on new technologies, platforms, and secret tips for distance teaching have ... -
Alpha Taxonomy of Eocene Primates from the Great Divide Basin, Wyoming
(East Carolina University, 2021-07-30)The identification of the alpha taxonomy of an extinct species is the first step towards understanding its evolutionary history and relationships with other organisms. Alpha taxonomy refers to the initial classification ... -
ALS AND FAMILY FUNCTIONING
(East Carolina University, 8/5/2020)Amyotrophic Lateral Sclerosis (ALS) is the most common progressive and fatal neurodegenerative disease and yet a cure remains unknown. Given the growing number of patients with ALS, it is imperative that behavioral health ... -
Alteration of AKT Activity Increases Chemotherapeutic Drug and Hormonal Resistance in Breast Cancer yet Confers an Achilles Heel by Sensitization to Targeted Therapy
(East Carolina University, 2008)The PI3K/PTEN/Akt/mTOR pathway plays critical roles in the regulation of cell growth. The effects of this pathway on drug resistance and cellular senescence of breast cancer cells has been a focus of our laboratory. ... -
Alteration of In Vivo Cellulose Ribbon Assembly by Carboxymethylcellulose and Other Polysaccharides
(East Carolina University, 1982)In vivo cellulose ribbon assembly by the Gram-negative bacterium Acetobacter xylinum can be altered by incubation in carboxymethylcellulose (CMC), a negatively charged water-soluble cellulose derivative, and also by ... -
Alterations in insulin action and contraction-mediated metabolism in myotubes derived from Roux-en-Y gastric bypass patients
(5/16/2016)Roux-en-Y gastric bypass (RYGB) surgery induces various metabolic benefits in severely obese (BMI> 40 kg/m2) individuals, including improved insulin action in peripheral tissues, most notably skeletal muscle, and remission ...