Browsing by Author "Johnke, Roberta M."
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American Ginseng Modifies 137Cs-Induced DNA Damage and Oxidative Stress in Human Lymphocytes
Lee, Tung-Kwang; O'Brien, Kevin F.; Wang, Weidong; Sheng, Chao; Wang, Tao; Johnke, Roberta M.; Allison, Ron R. (East Carolina University, 2009-01-01)The multifold bioactive medicinal properties of ginseng have been closely linked to its antioxidative ability, which is related to its ginsenoside content. Since the key mechanism of radiation-induced cell death and tissue ... -
COMPARATIVE ANALYSIS OF TWO HUMAN CANCER CELL LINES FOLLOWING EXPOSURE TO LOW DOSE RADIATION
Nangami, Gladys N. (East Carolina University, 2011)Over the past two decades, studies on the cellular response to very low dose radiation have been revolutionizing historically-held paradigms of cellular radioresponse. Indeed, a host of seemingly contradictory events have ... -
COMPARISON OF TWO HUMAN CELL LINES FOLLOWING EXPOSURE TO LOW DOSE RADIATION AND TREATMENT WITH SOYBEAN MISO AND ITS ACTIVE INGREDIENT GENISTEIN
Sattler, Jennifer A. (East Carolina University, 2013)Exposure to radiation is increasingly becoming a worldwide health issue. Because of this, the need for effective radioprotectors is critical. This need is not met by amifostine, the current "gold standard" in radioprotectors, ... -
EXPLORING THE BYSTANDER EFFECT FOLLOWING VERY LOW DOSE RADIATION
Hollis, Sarah Elizabeth (East Carolina University, 2010)Bystander effects are defined as the phenomenon in which unirradiated cells respond biologically when their neighbors are irradiated. The exact mechanisms of these cellular responses are still not known, especially in ... -
Radioprotective Effect of American Ginseng on Human Lymphocytes at 90 Minutes Post-irradiation: A Study of 40 Cases
Lee, Tung-Kwang; O'Brien, Kevin F.; Wang, Weidong; Johnke, Roberta M.; Sheng, Chao; Benhabib, Sidi Mohammed; Wang, Tao; Allison, Ron R. (East Carolina University, 2010-05)Backgroundâ Ionizing radiation (IR) initiates intracellular oxidative stress through enhanced formation of reactive oxygen species (ROS) that attack DNA leading to cell death. As the diversity of IR applied in medicine, ... -
The radioprotective effects of IL-1[alpha] on murine gastrointestinal tissue
Smith, Elizabeth S.