Browsing by Author "Spandidos, Demetrios A."

Now showing items 1-3 of 3

  • Analysis of the mutation in cutaneous melanoma patients with occupational sun exposure 

    Candido, Saverio; Rapisarda, Venerando; Marconi, Andrea; Malaponte, Graziella; Bevelacqua, Valentina; Gangemi, Pietro; Scalisi, Aurora; McCubrey, James A.; Maestro, Roberta; Spandidos, Demetrios A.; Fenga, Concettina; Libra, Massimo (2014-03)
    Sun-exposure is one of the risk factors associated with the development of a cutaneous neoplasm. In melanoma, the Ras-Raf-MEK-ERK (MAPK) signaling pathway is constitutively activated through multiple mechanisms, including ...

  • Analysis of the B-RAFV600E mutation in cutaneous melanoma patients with occupational sun exposure 

    Candido, Saverio; Rapisarda, Venerando; Marconi, Andrea; Malaponte, Grazia; Bevelacqua, Valentina; Gangemi, Pietro; Scalisi, Aurora; McCubrey, James A.; Maestro, Roberta; Spandidos, Demetrios A.; Fenga, Concettina; Libra, Massimo (2014)
    Sun-exposure is one of the risk factors associated with the development of a cutaneous neoplasm. In melanoma, the Ras-Raf-MEK-ERK (MAPK) signaling pathway is constitutively activated through multiple mechanisms, including ...

  • Cutaneous melanoma: From pathogenesis to therapy (Review) 

    Leonardi, Giulia C.; Falzone, Luca; Salemi, Rossella; Zanghi, Antonino; Spandidos, Demetrios A.; Mccubrey, James A. (2018-02-27)
    In less than 10 years, melanoma treatment has been revolutionized with the approval of tyrosine kinase inhibitors and immune checkpoint inhibitors, which have been shown to have a significant impact on the prognosis of ...