Browsing by Subject "Insulin sensitivity"
Now showing items 1-8 of 8
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Contractile activity restores insulin responsiveness in skeletal muscle of obese Zucker rats.
(East Carolina University, 1993-01-15)Both insulin and contraction stimulate glucose transport in skeletal muscle. Insulin-stimulated glucose transport is decreased in obese humans and rats. The aims of this study were (1) to determine if contraction-stimulated ... -
The effect of fasting on the activation in vivo of the insulin receptor kinase.
(East Carolina University, 1990-02-01)Fasting causes insulin resistance in liver and fat, and increases insulin sensitivity in muscle. We studied the response in vitro and in vivo to insulin of the insulin receptor tyrosine kinase in muscle and liver from 72 ... -
Exercise Training Amount and Intensity Effects on Metabolic Syndrome (From Studies of a Targeted Risk Reduction Intervention through Defined Exercise)
(East Carolina University, 2007-12-15)Although exercise improves individual risk factors of the metabolic syndrome (MS), there is little research on the effect of exercise on MS as a whole. The objective of this study was to determine how much exercise is ... -
Mechanism for Improved Insulin Sensitivity after Gastric Bypass Surgery
(East Carolina University, 2008-12)Context: Surgical treatments of obesity have been shown to induce rapid and prolonged improvements in insulin sensitivity. Objective: The aim of the study was to investigate the effects of gastric bypass surgery and the ... -
Modulation of IKKβ with AMPK Improves Insulin Sensitivity in Skeletal Muscle
(East Carolina University, 2008-11)Activation of the insulin receptor substrate (IRS)-1 is necessary for proper transduction of the insulin signal. IRS-1 serine312(human)/307(rodent) phosphorylation, however, results in disruption of this signal and subsequent ... -
The role of the proximal small intestine in improvements in diabetes resolution and insulin sensitivity following bariatric surgery in type 2 diabetes
(East Carolina University, 2011)Bariatric surgery is an effective, rapid, and durable treatment for obesity and type 2 diabetes mellitus (T2DM). Roux-en Y Gastric Bypass (RYGB) resolves T2DM in 80% of cases, while gastric banding (LAGB) resolves T2DM in ... -
The Effects of Aerobic and Resistance Training on Insulin Sensitivity in Primary Human Skeletal Muscle Cells
(East Carolina University, 2023-05-18)Insulin is a hormone that plays a role in the regulation of glucose homeostasis, through the regulation of blood glucose levels³⁶. Insulin sensitivity is defined as how well the body responds to insulin, and when this is ...