Browsing Physiology by Author "Tapscott, Edward B."
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Contractile activity restores insulin responsiveness in skeletal muscle of obese Zucker rats.
Dolan, Patricia L.; Tapscott, Edward B.; Dorton, Peter J.; Dohm, G. Lynis (East Carolina University, 1993-01-15)Both insulin and contraction stimulate glucose transport in skeletal muscle. Insulin-stimulated glucose transport is decreased in obese humans and rats. The aims of this study were (1) to determine if contraction-stimulated ... -
An in vitro human muscle preparation suitable for metabolic studies. Decreased insulin stimulation of glucose transport in muscle from morbidly obese and diabetic subjects.
Dohm, G. Lynis; Tapscott, Edward B.; Pories, Walter J.; Dabbs, David J.; Flickinger, Edward G.; Meelheim, Diane; Fushiki, Tohru; Atkinson, Samuel M.; Elton, Charles W.; Caro, Jose F. (East Carolina University, 1988-08)We have developed an in vitro muscle preparation suitable for metabolic studies with human muscle tissue and have investigated the effects of obesity and non-insulin-dependent diabetes mellitus (NIDDM) on glucose transport. ... -
Mechanism for Improved Insulin Sensitivity after Gastric Bypass Surgery
Bikman, Benjamin Thomas; Zheng, Donghai; Pories, Walter J.; Chapman, William H. H.; Pender, John R.; Bowden, Rita C.; Reed, Melissa A.; Cortright, Ronald N.; Tapscott, Edward B.; Houmard, Joseph A.; Tanner, Charles J.; Lee, Jihyun; Dohm, G. Lynis (East Carolina University, 2008-12)Context: Surgical treatments of obesity have been shown to induce rapid and prolonged improvements in insulin sensitivity. Objective: The aim of the study was to investigate the effects of gastric bypass surgery and the ...