Search
Now showing items 121-130 of 151
Muscle cell derived angiopoietin-1 contributes to both myogenesis and angiogenesis in the ischemic environment
(2015-05)
Recent strategies to treat peripheral arterial disease (PAD) have focused on stem cell based therapies, which are believed to result in local secretion of vascular growth factors. Little is known, however, about the role ...
Paternal diet and exercise epigenetically program energy expenditure and glucose metabolism in mouse offspring
(East Carolina University, 2014)
It is currently estimated that a third of Americans suffer from metabolic syndrome, which is an obesogenic disease shown to increase risk for developing type 2 diabetes (T2DM) by five-fold (Diabetes Care, 2012). The ...
Targeting the mitochondrial inner membrane to improve bioenergetics in the diseased heart
(East Carolina University, 2014)
Cardiovascular diseases continue to exact unparalleled economic and humanitarian costs across the globe. Manifestations of cardiovascular diseases include acute coronary syndromes and heart failure, both of which are ...
Nocturnal thoracoabdominal asynchrony in house dust mite-sensitive nonhuman primates
(2010)
Nocturnal bronchoconstriction is a common symptom of asthma in humans, but is poorly documented in animal models. Thoracoabdominal asynchrony (TAA) is a noninvasive clinical indication of airway obstruction. In this study, ...
Cardiovascular Outcomes Following Xenobiotic Pulmonary Exposures
(East Carolina University, 2017-07-06)
Cardiovascular disease remains the leading cause of mortality in the developed world. Over the past decades, investigations have demonstrated that pulmonary exposure to xenobiotic particulate matter promotes and exacerbates ...