Now showing items 1-5 of 5
Predifferentiated Embryonic Stem Cells Prevent Chronic Pain Behaviors and Restore Sensory Function Following Spinal Cord Injury in Mice
(East Carolina University, 2006)
Embryonic stem (ES) cells have been investigated in repair of the CNS following neuronal injury and disease; however, the efficacy of these cells in treatment of postinjury pain is far from clear. In this study, we evaluated ...
Transplantation of GABAergic Neurons but not Astrocytes Induces Recovery of Sensorimotor Function in the Traumatically Injured Brain
(East Carolina University, 2007-04-16)
Embryonic stem (ES) cells have been investigated in many animal models of injury and disease. However, few studies have examined the ability of pre-differentiated ES cells to improve functional outcome following traumatic ...
MicroRNA-431 regulates axon regeneration in mature sensory neurons by targeting the Wnt antagonist
MicroRNAs (miRNAs) are small, non-coding RNAs that function as key post-transcriptional regulators in neural development, brain function, and neurological diseases. Growing evidence indicates that miRNAs are also important ...
Molecular mechanisms of peripheral nerve regeneration: emerging roles of microRNAs
MicroRNAs are small non-coding RNAs that suppress gene expression through target mRNA degradation or translation repression. Recent studies suggest that miRNA plays an important role in multiple physiological and pathological ...