Browsing Dissertations and Theses by Title
Now showing items 286-305 of 4831
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AMP Deaminase 3 in Skeletal Muscle Atrophy: Regulation of Protein Degradation and Contractile Performance
(East Carolina University, 2015-11-23)Skeletal muscle atrophy is characterized by depressed cellular energetics, increased rates of protein degradation, contractile deficits and loss of muscle mass. A potential regulator of these impairments is the metabolic ... -
AMP Deaminase 3 knockout mice and loss of mitochondrial proteins and enzyme activity during denervation atrophy
(East Carolina University, 2018-07-17)Muscle atrophy leads to decrements in muscle function, partly attributable to decreased mitochondrial content. One controller of mitochondrial content is AMP-activated protein kinase (AMPK), which when bound by AMP activates ... -
AMP Deaminase 3 overexpression regulates cellular energetics and signaling for PGC-1α activation.
(East Carolina University, 2017-06-02)Skeletal muscles undergoing atrophy have decreased [ATP], PGC-1[alpha] expression, and mitochondrial content. This combination of findings is unexpected because decreased [ATP] is often associated with greater [AMP] and ... -
AN ALL HAZARDS, ALL AGENCIES, ALL PEOPLE APPROACH TO ASSESS LOCAL- LEVEL HOUSEHOLD EMERGENCY PREPAREDNESS AND COMMUNITY DISASTER RESILIENCE
(East Carolina University, 2022-11-30)Problem: Given the increasing frequency, intensity, and severity of disasters, and a gap in disaster research examining the interdependent systemic relationships between individuals and communities, we urgently need to ... -
AN ANALYSIS OF A PLAN TO IMPROVE THE GRADUATION RATES IN JOHNSTON COUNTY SCHOOLS
(East Carolina University, 2015-12-10)There have been limited qualitative case studies exploring effective strategies designed to improve graduation rates in rural school districts. Specifically, few studies have presented information based solely upon the ... -
AN ANALYSIS OF A STONE ARTIFACT CACHE FROM THE SHELOR SITE (31MG2051) IN MONTGOMERY COUNTY, NORTH CAROLINA
(East Carolina University, 2016-07-25)Prehistoric artifact cache discoveries are poorly understood archaeological phenomena. A few such occurrences consisting of groups of stone artifacts buried in forgotten underground pits are known in North Carolina. This ... -
AN ANALYSIS OF ALFRED SCHNITTKE'S POLYSTYLISM IN HIS STRING QUARTET NO. 3 (1983)
(East Carolina University, 2018-07-30)The study of polystylism and its role in the history of music is a relatively new idea; Alfred Schnittke is often regarded as the first true proponent of the term, and the bulk of his compositional output did not begin ... -
AN ANALYSIS OF THE IMPACT OF mCLASS: READING 3D ON STUDENTS’ READING ACHIEVEMENT IN SECOND GRADE
(East Carolina University, 2015-04-28)The purpose of this program evaluation was to research North Carolina’s adoption of mClass: Reading 3D to determine program effectiveness, how teachers use student data from the program to improve instructional practices, ... -
AN ANALYSIS OF THE PERCEPTIONS OF PARENTS AND EDUCATORS ON DARE COUNTY SCHOOLS’ SPANISH DUAL LANGUAGE IMMERSION PROGRAM
(East Carolina University, 2019-04-23)Bilingual education is an emerging trend that can be found in many American public schools. Increasingly, schools are looking towards dual language immersion programs to foster increased cultural awareness, stronger literacy ...