Browsing Dissertations and Theses by Author "Akula, Shaw M."
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A role for VEGFRs in regulating KSHV latency
Lambert, Phelps J. -
A Smad3/FoxO3 Transcriptional Relationship in the Regulation of Vascular Growth
Francisco, Jake (East Carolina University, 2019-06-05)Cardiovascular disease (CVD) is a multi-faceted pathological condition that continually ranks as the number one cause of morbidity and mortality in the United States and worldwide. Unfortunately, despite extensive basic ... -
Changes occuring [sic] on the cell surface during KSHV reactivation
Whitman, Audy G. -
Cigarette smoking abrogates angiogenesis :implications for Kaposi's sarcoma
Bryan, Benjamin A. -
Cigarette smoking abrogates angiogenesis :implications for Kaposi's sarcoma
Bryan, Benjamin A. -
DEFINING THE ABILITY OF SNAT NANOTHERAPEUTIC TO INHIBIT SARS-COV-2 INFECTION AND ALTER THE HOST MICRONOME TO INDUCE AN ANTIVIRAL CELLULAR ENVIRONMENT
Bauer, Anais (East Carolina University, 2023-12-07)MicroRNAs (miRNAs) are regulatory elements that canonically bind to target mRNAs, reducing translation and protein output. They are non-coding strands of RNA, roughly 18-25 nucleotides long, and are found in plants, animals, ... -
DISINTEGRIN-LIKE DOMAIN IN KSHV ENCODED gB IS A NECESSITY TO PROMOTE VIRUS LATENCY
Walker, Lia R. (East Carolina University, 2011)KSHV glycoprotein B (gB) is a lytic structural protein expressed on the envelope of mature virions and on the membrane of cells supporting lytic infection. Previous studies have identified that in addition to the role of ... -
FUNCTION OF DISINTEGRIN-LIKE DOMAIN OF KSHV gB IN REGULATING VIRUS INFECTION
Walker, Lia R. (East Carolina University, 2015-12-10)KSHV, also referred to as human herpesvirus-8 (HHV-8), is the eighth and latest identified human herpesvirus. It is the causative agent for a variety of malignancies namely Kaposi’s sarcoma (KS), primary effusion lymphoma ... -
MICRONOME AND KSHV INFECTION: IDENTIFICATION AND FUNCTIONAL CHARACTERIZATION OF CELLULAR MICRORNAS DURING VIRUS ENTRY
Hussein, Hosni Ahmed Mohamed (East Carolina University, 2018-04-17)Kaposi's sarcoma-associated herpesvirus (KSHV), is the most recently identified human herpesvirus and causes a variety of human malignancies. KSHV is etiologically associated with Kaposi's sarcoma (KS), primary effusion ... -
Novel Nano-Based Antibacterial Therapeutic Against Hospital Acquired Infection
Williams, Jordan E (East Carolina University, 2022-07-19)Rising nosocomial infections, also called hospital-acquired infections (HAIs), are of imminent public health concern as common antibiotics, such as ampicillin and kanamycin, are becoming less effective against bacterial ... -
Regulation of KSHV replication by glycoprotein B: chronicles of a virus and its host
Dyson, Ossie F. (East Carolina University, 2011)Kaposi's sarcoma-associated herpesvirus (KSHV), the causative agent of three cancers: Kaposi's sarcoma (KS), primary effusion lymphoma (PEL), and the plasmablastic form of multicentric Castleman disease (MCD), shares many ...