Browsing Dissertations and Theses by Author "Keene, Keith L."
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A Candidate Gene Study: Finding Associations between Recurrent Stroke and Genetic Variants of Five Folate-Mediated One Carbon Metabolism Pathway Genes
Mitchell, Nicole R. (East Carolina University, 2019-04-25)Stroke is the second leading cause of death in the world and fifth in the United States. Both in the United States and worldwide, stroke is the leading cause of disability. Stroke is a cerebrovascular event which results ... -
Integrative multi-omic analyses identify novel biomarkers for recurrent stroke in participants from the Vitamin Intervention for Stroke Prevention (VISP) clinical trial
Davis Armstrong, Nicole M. (East Carolina University, 2019-05-01)Background: Recurrent strokes are deadlier and more disabling than primary strokes and over 185,000 individuals in the US suffer a recurrent event each year. Current diagnostic and at-risk identification tools are inadequate ... -
Investigating Genetic Variants of the Folate One Carbon Metabolism (FOCM) Pathway for Associations with Recurrent Stroke and Measures of Homocysteine
Williams, Mitchell A. (East Carolina University, 2017-07-17)Stroke is currently the fifth leading cause of death and the leading cause of long-term disability in the United States. Stroke accounts for over 140,000 deaths annually and according to the Centers for Disease Control and ...