Browsing Dissertations and Theses by Author "Keiper, Brett D"
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HUMAN RNA METHYLTRANSFERASE METTL16 AFFECTS MULTIPLE CELL PROCESSES THROUGH DIFFERENTIAL FUNCTION OF ITS DOMAINS
Talic, Emily Satterwhite (East Carolina University, 2022-11-10)ABSTRACT In recent years, disease therapies have been developed to target specific RNA and protein expression changes in the affected cells/tissue. The RNA post-transcriptional modification, methyl-6-adenosine (m6A), has ... -
m6A’s Unique and Dynamic Role in Breast Cancer Progression
Dorgham, Mohammed Gamal (East Carolina University, 2023-07-18)Despite intense study, metastatic breast cancer is still the second leading cause of female death from cancer in the US. While many genetic lesions and environmental factors have been implicated in breast cancer progression, ...