Browsing Dissertations and Theses by Author "Kennedy, Anthony"
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A Calorimetric and Spectroscopic Study of the Interactions Between Model Lipid Membrane Bilayers and Simple Sugars
Pennington, Edward Ross (East Carolina University, 2015)It is well known that various organisms, such as the tardigrade, naturally use carbohydrates, particularly disaccharides, to help preserve their cell structural and functional integrity during freezing or dehydration. There ... -
Investigating Membrane Protection of Red Blood Cells in the Presence of Mono and Disaccharides at Hypothermic Storage Conditions
Hickman, Josie Annette (East Carolina University, 8/5/2020)The maximum approved storage time of red blood cells under hypothermic conditions is 42 days when treated with an appropriate additive solution. Here, we investigated the possible protective properties of various mono and ... -
Red Blood Cell Preservation Under Austere Conditions
Angermeier, Tori Marena (East Carolina University, 2023-01-05)In the United States, the maximum approved preservation time for red blood cells under hypothermic storage conditions is 42 days when treated with an appropriate additive solution, namely AS-1. In this investigation, we ... -
Using Fluorescence and Infrared Spectroscopy to Analyze the Interaction of Disaccharides with Lipid Bilayers
Angermeier, Tori Marena (East Carolina University, 2018-07-24)It is well known that sugars, such as trehalose, dehydrate lipid membranes based upon the Water Replacement Hypothesis. Here, we have investigated the interaction between different sugars (sucralose, sucrose, and trehalose) ... -
Using Fluorescent Probes to Study the Location and Interaction of Disaccharides within Lipid Bilayers
Barker, Morgan Elizabeth (East Carolina University, 2016-04-26)It is well known that certain organisms, such as the tardigrade, are capable of surviving extreme conditions including dehydration, freezing and / or oxygen deficiency. The tardigrades ability to withstand such extreme ...