Browsing Dissertations and Theses by Subject "Obesity--Physiological aspects"
Now showing items 1-5 of 5
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A Comparison of Lean and Obese Gait Characteristics of Children and Adults During Level Walking
(East Carolina University, 2010)Increased body mass affects gait kinematics and kinetics in adults. It is however unknown if increased body mass produces similar adaptations in children and adults. The duration of obesity in children is shorter than ... -
Effect of Acute Exercise or Fasting on Mitochondrial Function and High Fat Diet-Induced Insulin Resistance
(East Carolina University, 2009)A high-fat diet leads to an accumulation of lipid in skeletal muscle, and the development of both mitochondrial dysfunction and insulin resistance. Recently, our lab reported that lipid overload leads to elevated ... -
Effects of resveratrol and contractile activity in human skeletal muscle myotubes from severely obese individuals
(East Carolina University, 2016-07-25)The prevalence of obesity is exponentially increasing worldwide. Although strategies such as exercise, nutritional intervention, and pharmaceutical therapies including resveratrol have been extensively studied in lean or ... -
ENHANCED INSULIN SIGNALING FOLLOWING CONTRACTILE ACTIVITY IS BLUNTED IN MYOTUBES FROM SEVERELY OBESE INDIVIDUALS WITH OR WITHOUT TYPE 2 DIABETES
(East Carolina University, 2018-06-11)Introduction: Regular exercise has been known to improve insulin sensitivity in obese/ Type 2 Diabetic (T2D) individuals. However, some obese and T2D individuals do not respond well to regular exercise in their metabolic ... -
Metabolic Inflexibility in Skeletal Muscle With Obesity
(East Carolina University, 2009)The skeletal muscle of obese individuals has a reduced capacity to oxidize lipids. The hypothesis to be tested in this dissertation is that the ability to regulate lipid oxidation in response to lipid exposure is impaired ...