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Now showing items 151-160 of 221
Repair of Clustered DNA Lesions in Double Strand Break Repair Deficient Human Tumor Cells
(East Carolina University, 2010)
DNA-dependent protein kinase (DNA-PK) is a holoenzyme of three subunits, Ku70, Ku80, and the DNA-Pk catalytic subunit (DNA-PKcs). DNA-PK serves a role in non-homologous end joining to repair double stranded breaks, and ...
The Brucella abortus alkyl hydroperoxide reductase complex (AhpCD) is the primary scavenger of endogenous hydrogen peroxide and the ahpCD operon is regulated in response to endogenous hydrogen peroxide.
(East Carolina University, 2010)
Brucella abortus is a facultative intracellular pathogen that causes abortion and infertility in cattle and relapsing fever in humans. These bacteria reside and replicate inside macrophages during infection, and the ability ...
The Borderlands in Puerto Rico : Creating New Identities
(East Carolina University, 2010)
Gloria Anzaldúa's Borderlands/La Frontera is one of the most influential books on border theory, but because her theories are rooted in her experiences in the Rio Grande Valley between Texas and Mexico, they cannot be ...
Tissue Salvage in the Non-reperfused Myocardium Mediated by (the absence of the circadian rhythm gene) mPer2 and (the receptor tyrosine kinase) EphrinA1
(East Carolina University, 2010)
Alterations in circadian rhythm have been associated with numerous cardiovascular pathologies. In project 1, we tested the hypothesis that functional mutation of the Per2 circadian clock gene would provide cardioprotection ...
The "Bohemian Girl" Project : A Steam Launch Study
(East Carolina University, 2010)
The objective of this thesis is to research Lake Waccamaw's maritime activity from 1880 to 1910. Similar research projects concerning remote lakes, like Lake Waccamaw, were conducted in areas only accessible after the ...
Breathing Rate, Pattern, and Heart Rate During Baseline Recording and Painful Electrodermal Stimulation-Induced Anxiety
(East Carolina University, 2010)
Background: One common treatment for anxiety is breathing retraining (BRT), but evidence of its efficacy and effectiveness is mixed, and the mechanisms are not well-understood. To date, no study has examined breathing ...
Effects of Alternative Seating on the Academic Engagement of Children With Autism
(East Carolina University, 2010)
Students with sensory integration deficits may display a hyper or hyposensitivity to sensory information and lack the ability to modulate that input in socially appropriate ways. Therapy balls as a sensory integration ...
Satisfaction with Life and Biopsychosocial-Spiritual Health among Underserved Patients with Diabetes
(East Carolina University, 2010)
The prevalence of type 2 diabetes continues to escalate, especially among vulnerable and underserved populations (CDC, 2008); however, the current landscape of literature has not kept pace with the trends of those most ...
Relationship Between Test Performance of Students with Learning Disabilities and the Poverty Levels of Their Schools
(East Carolina University, 2010)
The purpose of this causal-comparative study was to explore the relationship between the achievement of students with learning disabilities (LD) and the socioeconomic make-up of their schools. The research was guided by ...
'Because You Got to Have Heat' : Energy Poverty and Weatherization in Eastern North Carolina
(East Carolina University, 2010)
Energy poverty is the condition in which a household is unable to maintain its indoor temperature at a level that allows for a healthy or comfortable lifestyle. Much energy poverty literature has examined the problem ...