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Influence of Climatic Oscillations on Indian Ocean Tropical Cyclone Energy
(East Carolina University, 2014)
Tropical Cyclones form in 4 independent regions of the Indian Ocean Basin ranging from the Arabian Sea, Bay of Bengal, Western South Indian, and Eastern South Indian Ocean. These cyclones lead to distinct patterns in their ...
Trauma, Coping, & the Couple Relationship : An Investigation of Pregnant Couples' Biopsychosocial-Spiritual Health
(East Carolina University, 2014)
Pregnancy and trauma are each complex biopsychosocial-spiritual processes with implications for the couple relationship, but there is not enough research on the ways that the two constructs are connected. Two articles were ...
SEAFARING WOMEN : An Investigation of Material Culture for Potential Archaeological Diagnostics of Women on Nineteenth-Century Sailing Ships
(East Carolina University, 2014)
During the 19th century, women went to sea on sailing ships. Wives and family accompanied captains on their voyages from New England. They wrote journals and letters that detailed their life on board, adventures in foreign ...
THE LIVED EXPERIENCE OF COUPLES AFTER BARIATRIC SURGERY : A QUALITATIVE DESCRIPTION
(East Carolina University, 2014)
Obesity is a worldwide epidemic. Diet, exercise, and medical therapies alone have not been enough to stem the tide of this epidemic. Bariatric surgery has been found not only to be the most effective intervention for ...
Investigation of the Zinc binding region of Prothymosin-alpha : A spectroscopic and thermodynamic approach to study metal binding in Intrinsically disordered proteins
(East Carolina University, 2014)
The goal of this study is to provide a deeper insight into how metals bind intrinsically disordered proteins (IDPs) by taking zinc binding to prothymosin-alpha as a case study. The involvement of metals in several diseases ...
Targeting the mitochondrial inner membrane to improve bioenergetics in the diseased heart
(East Carolina University, 2014)
Cardiovascular diseases continue to exact unparalleled economic and humanitarian costs across the globe. Manifestations of cardiovascular diseases include acute coronary syndromes and heart failure, both of which are ...
A descriptive exploratory study on how nurse educators use digital stories in the classroom
(East Carolina University, 2014)
This study examines the experiences of 12 nurse educators using digital stories in undergraduate nursing courses. Two issues were explored: 1) How and for what purpose are nurse educators incorporating digital stories in ...
Developmental lead exposure and the exacerbation of Alzheimer's pathology: an immunological analysis
(East Carolina University, 2014)
Early neuroimmune dysfunction may play a driving role in the etiopathology of Alzheimer's disease (AD), stemming from the hypothesis that many late-stage adult diseases have an early-life basis. Here we explore whether ...
Interrelated role of Notch signaling and mTORC pathways in prostate cancer cell survival and growth
(East Carolina University, 2014)
Prostate cancer is currently the second highest leading cause of
cancer death in men. Notch is a transmembrane receptor protein that
is part of a signaling pathway necessary in the normal development of
the prostate. ...
N-3 polyunsaturated fatty acids differentially enhance B-cell mediated immunity in lean and obese mice
(East Carolina University, 2014)
Docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) are
bioactive n-3 polyunsaturated fatty acids (PUFAs) in fish oil that
exert immunomodulatory effects. The general paradigm suggests n-3
PUFAs exert immunosuppressive ...