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Motility and chemotaxis in the Lyme disease spirochete Borrelia burgdorferi : role in pathogenesis
(East Carolina University, 2016-08-18)
Lyme disease is the most prevalent vector-borne disease in United States and is caused by the spirochete Borrelia burgdorferi. The disease is transmitted from an infected Ixodes scapularis tick to a mammalian host. B. ...
Press Gang Revisited: Polarization, Nuance, and the Study of Impressment in the Royal Navy
(East Carolina University, 2016-12-15)
Over the course of the long eighteenth century, Britain grew from an island nation with limited colonial holdings to a transatlantic imperial power. Because of this territorial expansion, the Royal Navy increased dramatically ...
Predicting length of treatment involvement of substance using perinatal women in an integrated inpatient healthcare program
(East Carolina University, 2016-12-16)
Services for perinatal (pregnant and one year postpartum) women are limited, and inpatient settings where women receive substance abuse services specific to the perinatal population, although ideal, are rare in eastern ...
PERCEIVED EFFECTIVENESS OF A DRIVING AND COMMUNITY MOBILITY BOOTCAMP FOR INDIVIDUALS WITH AUTISM SPECTRUM DISORDER
(East Carolina University, 2016-12-15)
This study was designed to determine the perceived effectiveness of a driving and community mobility Bootcamp for young adults with high functioning autism spectrum disorder (HFASD). Seven participants and their parents ...
Fundamental and Applied Studies on Chromatographic Separation of Cold Drugs and Skincare Creams and Extraction of Salvia miltiorrhiza using Subcritical Water
(East Carolina University, 2014)
Subcritical water chromatography (SBWC) and subcritical water extraction (SBWE) are two green techniques that use subcritical water as the sole solvent for separations, thus eliminating the use of toxic and expensive organic ...
N-3 polyunsaturated fatty acids differentially enhance B-cell mediated immunity in lean and obese mice
(East Carolina University, 2014)
Docosahexaenoic acid (DHA) and eicosapentaenoic acid (EPA) are
bioactive n-3 polyunsaturated fatty acids (PUFAs) in fish oil that
exert immunomodulatory effects. The general paradigm suggests n-3
PUFAs exert immunosuppressive ...
Investigation of the Zinc binding region of Prothymosin-alpha : A spectroscopic and thermodynamic approach to study metal binding in Intrinsically disordered proteins
(East Carolina University, 2014)
The goal of this study is to provide a deeper insight into how metals bind intrinsically disordered proteins (IDPs) by taking zinc binding to prothymosin-alpha as a case study. The involvement of metals in several diseases ...
Targeting the mitochondrial inner membrane to improve bioenergetics in the diseased heart
(East Carolina University, 2014)
Cardiovascular diseases continue to exact unparalleled economic and humanitarian costs across the globe. Manifestations of cardiovascular diseases include acute coronary syndromes and heart failure, both of which are ...
A descriptive exploratory study on how nurse educators use digital stories in the classroom
(East Carolina University, 2014)
This study examines the experiences of 12 nurse educators using digital stories in undergraduate nursing courses. Two issues were explored: 1) How and for what purpose are nurse educators incorporating digital stories in ...
Developmental lead exposure and the exacerbation of Alzheimer's pathology: an immunological analysis
(East Carolina University, 2014)
Early neuroimmune dysfunction may play a driving role in the etiopathology of Alzheimer's disease (AD), stemming from the hypothesis that many late-stage adult diseases have an early-life basis. Here we explore whether ...