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TMEFF2 is an epigenetic modulator that promotes androgen independent growth in castration-resistant prostate cancer cells
(East Carolina University, 2014)
While the ability to detect PCa has improved significantly due to PSA screenings, the survival rate for men diagnosed with PCa has remained stagnant, and the disease remains the second leading cause of cancer related deaths ...
The Acquisition of a Plastid by Haptophytes, Cryptophytes, and Photosynthetic Heterokonts
(East Carolina University, 2014)
Red algae and green plants are known to have obtained their photosynthetic organelles, or plastids, through the endosymbiotic adoption of cyanobacteria. It is still widely debated as to how other eukaryotic alga such as ...
PROGRAM EVALUATION OF READING PLUS : STUDY OF THE IMPACT ON READING ACHIEVEMENT FOR MIDDLE SCHOOL STUDENTS IN MOORE COUNTY SCHOOLS
(East Carolina University, 2014)
The Superintendent of Moore County Schools requested a program evaluation to support the use of the Reading Plus program for reading intervention. The schools or administrators across the system had chosen a variety of ...
The Relationship Between Micro-Counseling Skills and Clinical Attendance
(East Carolina University, 2014)
Project Working Recovery (PWR) was a clinic that operated at East Carolina University in the Addictions and Rehabilitation Studies Department from April 2008 until June 2009. Intake procedures were followed and clients who ...
The Effects of Crude Oil and Chemical Dispersant Exposure on Danio rerio (zebrafish) Embryonic Development
(East Carolina University, 2014)
Crude oil has been shown to cause defects in cardiovascular development in a variety of teleost species. We used the zebrafish, Danio rerio as a model to test the effects of oil and dispersant on cardiac development and ...
Spatial Ecology and Seasonal Habitat Use of the King Rail (Rallus elegans) along the Atlantic Coast
(East Carolina University, 2014)
TThe King Rail (Rallus elegans) continues to experience population declines throughout its range. Due to its secretive nature and occupancy of densely vegetated marshes, little is known about the behavior and ecology of ...
Spatial and Temporal Evaluation of Dune, Beach and Nearshore Bar Interactions : Cape Cod, MA
(East Carolina University, 2014)
Coastal features and processes interact with each other, producing complex patterns of shoreline changes in different beach segments. Coastal dune systems have been studied in detail, looking at their evolution through ...
Layered regulation of a pathway capable of altering quinolone production in Pseudomonas aeruginosa
(East Carolina University, 2014)
Pseudomonas aeruginosa is a gram negative opportunistic pathogen which commonly infects hospitalized patients and those afflicted with cystic fibrosis. P. aeruginosa communicates intercellularly via a system of small ...
The immune and neurological impacts of developmental Bisphenol A exposure in a C57bl/6 mouse model
(East Carolina University, 2014)
Environmental exposure to exogenous agents during critical time points of development may be associated with the onset of deleterious effects, including immune and neurological disorders. Numerous studies have shown that ...
Holocene Stratigraphy and Paleoenvironmental Change of Pamlico Sound, North Carolina, USA
(East Carolina University, 2014)
Understanding how coastal systems respond to changes in climate is becoming more important due to the current increased rate of sea-level rise and possible increased hurricane intensity in the future. While coastal ecosystems ...