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Elucidating Gene Function with the use of Genome Wide Association Study (GWAS)
(East Carolina University, 2015)
DNA replication and cell proliferation are intensely studied subjects. There have been countless experiments and hours put into better understanding how DNA is replicated and compacted, and how cells are able to proliferate ...
Analysis of scn5Laa and scn5Lab Gene Function in Danio rerio (Zebrafish) Heart Development through TALENs/CRISPR-CAS9-mediated Gene Knockout
(East Carolina University, 2015)
Research in our laboratory is focused on understanding the molecular developmental genetic effects of crude oil exposure on vertebrate embryogenesis. Our research has demonstrated that exposure of zebrafish embryos to ...
Fishing For The Evolutionary Bases Of Female Ornamentation
(East Carolina University, 2015)
Sexual dimorphism, or phenotypic differentiation of the sexes, is widespread amongst animals. It is understood mainly in the context of sexual selection, i.e. selection on mating success, with such selection typically ...
Evaluating The Essential Functions Of The Replication Factor Mcm10 In Drosophila Melanogaster
(East Carolina University, 2015)
Often referred to as miraculous, life as we know depends not upon miracles but on a series of highly orchestrated and regulated biochemical processes collectively known as the cell cycle. It is through these series of ...
Genetic control of cell fate specification in Caenorhabditis elegans germline.
(East Carolina University, 2015)
The precise regulation of germ cell fates (sperm or oocyte) lies at the heart of reproduction and fertility. The nematode Caenorhabditis elegans hermaphrodites produce a discrete number of sperm during larval development ...
General And Device-Specific Quality Of Life In Arrhythmogenic Right Ventricular Cardiomyopathy Patients : The Impact Of Shock And Sex
(East Carolina University, 2015)
Background: Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a heritable cardiac condition that weakens the heart and results in frequent and often life-threatening arrhythmias, requiring the placement of an ...
Genome-Wide Identification And Expression Analysis Of TCP Transcription Factors In Cotton
(East Carolina University, 2015)
TCP proteins are plant-specific transcription factors known to perform a variety of physiological functions during plant growth and development. In the current study, we performed for the first time the comprehensive ...