Dissertations and Theses: Recent submissions
Now showing items 21-40 of 4831
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SPATIAL AND PLANAR DYSREGULATION OF RHOGTPASES IN HUMAN AND ALZHEIMER’S DISEASE MOUSE MODEL
(East Carolina University, 2023-11-27)Rho proteins belong to the Ras superfamily of small GTPases. In humans, the Rho family of GTPases contains 20 members out of which the most studied Rho proteins are RhoA, Rac1, and Cdc42. Rho signaling is known to regulate ... -
Age-Related Diagnostic Considerations and Neurocognitive Impairment Implications for Insomnia Disorder
(East Carolina University, 2023-12-01)Insomnia affects 10-30% of the U.S. population and can be found across varying stages of life. While it has previously been shown that the addition of quantitative indices would be helpful for distinguishing between sleep ... -
Adapt & Overcome: Hypoxia Resistance is a Novel Phenotype of the Flexor Digitorum Brevis Skeletal Muscle
(East Carolina University, 2023-11-30)Skeletal muscle comprises the largest mammalian organ system by mass that enables movement, respiration, and thermogenesis. Each of these processes requires the presence of molecular oxygen (O2). Inadequate O2 bioavailability ... -
A UNIQUE MITOCHONDRIAL BIOENERGETIC PATHWAY UNDERLIES ACUTE MYELOID LEUKEMIA SURVIVAL AND CHEMORESISTANCE
(East Carolina University, 2023-12-01)In his early research on cancer cell metabolism, Otto Warburg made the hypothesis that the respiration of cancer cells has become damaged. The insult to cancer cell respiration, Warburg proposed, was either 1) a decrease ... -
IMPLEMENTATION OF A PARENT-LED COMBINED GROWTH-MINDSET AND HOME LITERACY INTERVENTION: A PILOT STUDY
(East Carolina University, 2023-11-30)This pilot study examined the implementation feasibility and preliminary effectiveness of a combined growth-mindset and literacy intervention delivered in the home by parents and guardians. The study was completed in two ... -
Development of Engaging Whiteboard Videos to Support Head Start Teachers’ Understanding of Evidence-based Strategies for Teaching Preschool Children (3-5 years) Science in the Context of Healthy Eating
(East Carolina University, 2023-12-07)Learning Objective: Identify Head Start teachers’ and relevant professionals’ perceptions of whiteboard videos designed to support understanding evidence-based strategies for teaching preschool children (3-5 years) science ... -
Examining Visual Processing Reaction Time As A Predictor For Driving Fitness
(East Carolina University, 2023-12-04)Rationale: As a complex IADL, driving is essential for social participation and quality of life. As such, it should be addressed by occupational therapy practitioners. Visual processing speed is a critical component of ... -
EXAMINING MULTI-TASKING ABILITY ON AN INTERACTIVE DRIVING SIMULATOR TASK TO DIFFERENTIATE BETWEEN FIT AND UNFIT DRIVERS
(East Carolina University, 2023-12-05)Rationale: Driving is an important, complex instrumental activity of daily living (IADL) with one of the most important skills being able to multitask. Multitasking is a skill assessed by few standardized assessments. The ... -
EXPLORING HEAD START TEACHERS' PERCEPTIONS OF SCIENCE IN PRESCHOOL EDUCATION
(East Carolina University, 2023-12-07)The lowest-performing learning domain, particularly among low-income families, has been identified as science education. Preschool science education has advantages that are well known, but more research is needed to ... -
Feasibility and Acceptability of a Values-Based Telehealth Intervention to Promote Adherence in Cardiopulmonary Rehabilitation Patients
(East Carolina University, 2023-12-07)Background: Current research indicates an ongoing need to identify interventions to promote Cardiopulmonary Rehabilitation (CVPR) participation, as participation in CVPR remains low despite positive effects on health ... -
INTERANNUAL VARIABILITY IN MORPHOMETRIC CONDITION OF LARVAL FISH AS A FUNCTION OF ENVIRONMENTAL VARIABLES IN BEAUFORT, NC
(East Carolina University, 2024-01-05)Recruitment can vary by several orders of magnitude and can be unpredictable from year-to-year, with its variability influenced by oceanic conditions experienced by fish larvae. Variations in larval abundance and condition ... -
Population Dynamics in a Mid-Atlantic Breeding Population of King Rails (Rallus elegans) and Comparative Genomic Diversity Across Their Range
(East Carolina University, 2024-01-05)King rail (Rallus elegans) populations have experienced severe declines throughout their range over the past half a century. As an obligate freshwater marsh bird, the king rail relies upon extensive, high-quality wetlands ... -
What's Wrong with a Rumor? Workplace Undermining and Customer-Oriented Outcomes
(East Carolina University, 2023-12-05)The purpose of this study was to examine the customer-oriented outcomes of supervisor and co-worker undermining, specifically, examining the differential impact of supervisor and co-worker undermining on customer- and ... -
“Stripped Clean by Wind and Water”: Historical and Archaeological Investigation of a Provincetown Plum-Pudding Whaling Company and its Reaction to a Dimming Industry
(East Carolina University, 2023-12-07)Industry decline after the 1859 discovery of petroleum prompted American whalers to adopt innovative strategies for survival, such as plum-pudding whaling. Characterized by short, Atlantic expeditions, it minimized risk ... -
EXPERIMENTAL DETERMINATION OF THERMOPHYSICAL PROPERTIES IN SUPERCRITICAL HEAT EXCHANGERS
(East Carolina University, 2023-12-07)An ECU team designed, built, and is testing a pilot-scale supercritical water desalination (SWD) system that processed brine discharge from conventional desalination systems. The system completely separates the solid salts ... -
Solutions of an Inhomogeneous MADE using an Analysis of Wavelet Coefficients
(East Carolina University, 2023-12-08)In this paper solutions to an Inhomogeneous Multiplicatively Advanced Differential Equation (MADE) of the form $y^\prime(t) - Ay(qt)=f(t)$, for $q>1$ and certain functions $f(t)\in \L^2(\R)$, are provided. Such solutions ... -
Pedagogical Approaches to the Instruction of Ethics in Lower-Level Undergraduate Professional Writing Courses
(East Carolina University, 2023-12-04)The following report centers on ethics instructional methods in undergraduate professional writing courses. The literature review covers the instructional practices favored by professors of upper-level and graduate ... -
Comparing Clinical Judgment Competency Between Accelerated and Traditional Bachelor of Science in Nursing Students during High-fidelity Simulation
(East Carolina University, 2023-12-01)ABSTRACT Background: Evidence suggests that competency in clinical judgment may be lacking in new graduate nurses. Graduates from accelerated baccalaureate nursing (ABSN) programs have even less time to develop clinical ... -
UNDERSTANDING TRAUMA SYMPTOMATOLOGY AND OCD: SHARED COGNITIVE ERRORS AND EMOTIONS
(East Carolina University, 2023-12-07)Although there is a well-documented link between post-traumatic stress disorder (PTSD) and obsessive-compulsive disorder (OCD), there is much that remains unknown about this relationship. Comorbid PTSD and OCD are linked ... -
TEACHING IN RURAL NORTH CAROLINA: THE IMPACT OF BEGINNING TEACHER SUPPORT ON TEACHER RETENTION
(East Carolina University, 2024-01-04)With research supporting that teachers have the greatest effect on student achievement, it is imperative that highly qualified teachers are retained while new teachers are recruited to the profession. The purpose of this ...