Browsing Dissertations by Submit Date
Now showing items 101-120 of 1044
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Investigating Non-Tight Junction Functions of Claudin-7: Regulating Large Intestine Stem Cell Functions and Niche Maintenance, and Junctional Protein Nanoarchitecture
(East Carolina University, 2022-12-12)Edit this abstract. -
Retrospective Risk Assessment of Forestry Workers in the United States: Injuries, Fatalities, and Hazards Impacting Occupational Health
(East Carolina University, 2022-12-02)Forestry (including logging) is one of the most hazardous occupations due to environmental, ergonomic, chemical, mechanical, mental, and physical components of the job. In the United States (US), workplace injuries account ... -
How Telework Influences Employee Productivity and Health
(East Carolina University, 2022-12-20)This study had three primary aims, the first of which was to create and evaluate a novel measure of telework based on the conceptualization of Kossek, Lautsch, & Eaton, (2006). Subsequently, this study produced the ... -
Accuracy of Wet Bulb Globe Temperature (WBGT) Obtained from Regional Weather Station Data for Agricultural Settings in Eastern North Carolina as Proxy for WBGT Obtained from Local Heat Stress Monitors
(East Carolina University, 2022-12-01)Introduction: Agricultural workers are at high risk of suffering from heat stress and subsequently developing heat-related illnesses (HRIs) due to the outdoor nature of their work. This risk can be exacerbated in hot, ... -
Discovering mechanisms during spermatogonial differentiation that prepare male germ cells for meiosis
(East Carolina University, 2022-12-05)Spermatogenesis, the male germ cell maturation process, allows men to become and remain fertile for decades. Male fertility relies on fate decisions of different types of spermatogonia – spermatogonial stem cells maintain ... -
Evolution of olfactory receptors in birds
(East Carolina University, 2022-12-05)Olfaction is an evolutionary ancient sensation, and is the perception and interpretation of chemical stimuli from surrounding air or water. Olfaction is an essential sensory modality for nearly all animals, and is used to ... -
TLR-4 agonism induces CD25+ MHCIIhigh dendritic cells in association with tolerogenic antigen recognition
(East Carolina University, 2022-12-06)Autoimmune disease is a result of the breakdown in immunological self-tolerance leading to destruction of self-tissues mediated by the aberrant immune attack. In Multiple Sclerosis (MS), CD4+ T cells mediate destruction ... -
Red Blood Cell Preservation Under Austere Conditions
(East Carolina University, 2023-01-05)In the United States, the maximum approved preservation time for red blood cells under hypothermic storage conditions is 42 days when treated with an appropriate additive solution, namely AS-1. In this investigation, we ... -
The Lived Experience of Nursing Staff in Skilled Nursing Facilities: Identification of Urinary Tract Infection in Residents
(East Carolina University, 2022-12-01)Annually, 50-70% of skilled nursing facility (SNF) residents receive at least one antibiotic, with up to 75% of those prescribed inappropriately. One-third of the antibiotic prescriptions are ordered to treat urinary tract ... -
The Influence of Orthodontic Appliances on Magnetic Resonance Imaging of the Velopharynx
(East Carolina University, 2022-12-08)Magnetic resonance imaging (MRI) is becoming increasingly valuable among cleft palate craniofacial teams in patients with velopharyngeal insufficiency (VPI). One hindrance to the growing use of MRI among the cleft population ... -
AN ALL HAZARDS, ALL AGENCIES, ALL PEOPLE APPROACH TO ASSESS LOCAL- LEVEL HOUSEHOLD EMERGENCY PREPAREDNESS AND COMMUNITY DISASTER RESILIENCE
(East Carolina University, 2022-11-30)Problem: Given the increasing frequency, intensity, and severity of disasters, and a gap in disaster research examining the interdependent systemic relationships between individuals and communities, we urgently need to ... -
Skeletal Muscle Purine Nucleotide Degradation and Atrophy: Cause or Consequence of Increased Uric Acid Production
(East Carolina University, 2022-07-26)Elevated serum uric acid is a risk factor for mortality in diseases and critical illnesses associated with skeletal muscle atrophy. Uric acid is generated by xanthine oxidoreductase (XOR) and XOR inhibitors can partially ... -
A Wzx-Wzy-like Polysaccharide Biosynthetic Pathway Contributes to Virulence in Brucella abortus 2308 through an Unknown Mechanism
(East Carolina University, 2022-08-05)Brucella abortus is an intracellular pathogen that causes spontaneous abortion in cattle and undulant fever in humans. As a member of the a-proteobacteria, B. abortus is closely related to the bacterial species Caulobacter ... -
Equity and Advanced Placement: Examining a School-Based Initiative to Remove Enrollment Barriers for African American Stuents
(East Carolina University, 2022-08-18)ABSTRACT Nydra Sade’ Jones. EQUITY AND ADVANCED PLACEMENT: EXAMINING A SCHOOL-BASED INITIATIVE TO REMOVE ENROLLMENT BARRIERS FOR AFRICAN AMERICAN STUDENTS (Under the direction of Dr. Marjorie Ringler). Department of ... -
RESTORATIVE JUSTICE: IMPLEMENTING SUSTAINABLE RESTORATIVE PRACTICES IN A K-12 SCHOOL
(East Carolina University, 2022-08-19)The purpose of this research is to describe how sustainable restorative practices focused on the intention of using inclusive school leadership, curriculum, wrap around supports, transformative community engagement, high ... -
Counselors’ Attitudes Toward Sex Trafficking: A Quantitative, National Analysis
(East Carolina University, 2022-06-03)For more than 20 years, the pervasive problem of sex trafficking has garnered increasing attention in research, advocacy, and legislation. The cumulative research focuses on the trafficking of women and girls based on the ... -
Lèvy noise induced steady states
(East Carolina University, 2022-06-08)Systems far from equilibrium organize themselves to accommodate energy throughput. It is also in these nonequilibrium systems where noise has often been found to follow alpha-stable distributions, commonly called Lèvy ... -
The Differential Roles of pH sensing G-Protein Coupled Receptors in Inflammation and Cancer
(East Carolina University, 2022-12-13)Intestinal inflammation is a burdening disease that may occur due to an aberrative immune response to certain drugs, infections, genetics, or unknown environmental factors. Inflammatory bowel disease (IBD) is of special ... -
HUMAN RNA METHYLTRANSFERASE METTL16 AFFECTS MULTIPLE CELL PROCESSES THROUGH DIFFERENTIAL FUNCTION OF ITS DOMAINS
(East Carolina University, 2022-11-10)ABSTRACT In recent years, disease therapies have been developed to target specific RNA and protein expression changes in the affected cells/tissue. The RNA post-transcriptional modification, methyl-6-adenosine (m6A), has ... -
NARROWING THE EDUCATIONAL INEQUITY GAP FOR PREGNANT AND PARENTING COLLEGE STUDENTS THROUGH FACULTY ENGAGEMENT
(East Carolina University, 2022-10-21)Pregnant and parenting college students often face additional barriers when completing their studies. One specific barrier is the lack of support from their educational institutions. This study focused on how college faculty ...