Browsing Dissertations by Type"Doctoral Dissertation"
Now showing items 461-480 of 1037
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Identification of Factors Associated with the Development and Decay of Heterologous Tolerance to Morphine in the Guinea Pig
(East Carolina University, 2016-05-03)It is believed that the heterologous tolerance that develops upon chronic exposure to morphine is the result of adaptive changes in the cellular signaling pathways associated with the [mu] opioid receptor. Proposed adaptive ... -
Identification of galectin-1 as a marker for claudin-low breast cancer and implications for tumor progression
(East Carolina University, 2024-01-04)Triple-negative breast cancer (TNBC) is an aggressive subtype of breast cancer. Patients with TNBC have a high rate of metastasis and mortality due to the lack of targeted therapies and resistance to chemotherapy. This ... -
IDENTIFICATION OF GEOCHEMICAL TRACERS WITHIN BIOMINERALS OF JUVENILE AND LARVAL MERCENARIA MERCENARIA : IMPLICATIONS FOR MODELING LARVAL DISPERSAL
(East Carolina University, 2013)This study was designed to investigate the application of geochemical signals within biominerals to identify site fidelity and natal origin of the commercially valuable bivalve Mercenaria mercenaria. My first study ... -
IDENTIFYING AN APPROPRIATE STRUCTURE TO SERVE ALTERNATIVE STUDENTS WITH STREET GANG AFFILIATION IN AN EFFORT TO INCREASE THE GRADUATION RATE AND ACADEMIC PROFICIENCY OF THE STUDENTS AT AN ALTERNATIVE HIGH SCHOOL IN SOUTHEASTERN NORTH CAROLINA
(East Carolina University, 2015-04-29)The purpose of this study was to identify an appropriate structure to successfully serve all alternative students, but especially those with street gang affiliation, in an effort to increase the graduation rate and academic ... -
Identifying the missing piece of suicide prevention : Formative risk assessment
(East Carolina University, 2014)Suicide is the third leading cause of death among adolescents and young adults (Centers for Disease Control [CDC], 2011). However, no evidence-based suicide prevention programs currently exist that utilize formative ... -
Identifying the unmet behavioral health needs that resettled refugee youth present within primary health care settings
(East Carolina University, 2019-07-24)The following is a six-chapter dissertation explores the behavioral health needs of resettled refugee youth in primary health care settings. All six chapters were based in Urie Bronfenbrenner's Ecological Systems Theory. ... -
IL-15 : A NOVEL REGULATOR OF LIPOLYSIS IN HUMANS?
(East Carolina University, 2014)Interactions between and within organ systems such as skeletal muscle (SkM) and adipose tissue (AT), via immune cell signaling factors (cytokines), may regulate the development of obesity. The increased expression and ... -
The immune and neurological impacts of developmental Bisphenol A exposure in a C57bl/6 mouse model
(East Carolina University, 2014)Environmental exposure to exogenous agents during critical time points of development may be associated with the onset of deleterious effects, including immune and neurological disorders. Numerous studies have shown that ... -
The Impact of a Vocational Counseling Based Substance Abuse Intensive Outpatient Program upon Work and Well-Being: A Pilot Study
(East Carolina University, 2011)Even though recovery from Substance Use Disorders (SUDs) involves changes among a number of life domains, services have traditionally focused on abstinence from substances. Cursory attention is placed on holistic treatment ... -
THE IMPACT OF ALTERNATE ASSESSMENTS AND STANDARDS-BASED IEPS ON CLASSROOM INSTRUCTION AND STUDENT ACHIEVEMENT
(East Carolina University, 2010)The U.S. Congress has passed several laws since 1997 in order to ensure the students with disabilities have an opportunity to learn and access the general curriculum. States now include students with disabilities in state ... -
Impact of Auditory Training on Speech Perception and Cognitive Abilities in Older Adults with Hearing Loss
(East Carolina University, 2011)The current study explored the impact of short term auditory training (LACE-Degraded) and auditory-cognitive training (LACE 4.0) on speech perceptual and cognitive measures in older adults with mild-moderate sensorineural ... -
Impact of Educational Messages on Patient Acceptance of Male Medical Students in OB-GYN Encounters
(East Carolina University, 2014)Medical student education in obstetrics and gynecology (OB-GYN) is an essential part of training and involves direct patient care experiences (APGO, 2012a; Harrell et al., 1993). However, for male students difficulties ... -
IMPACT OF INTRINSIC AEROBIC EXERCISE CAPACITY ON CARDIOVASCULAR OUTCOMES FOLLOWING VARIOUS FORMS OF CARDIOVASCULAR STRESS
(East Carolina University, 2020-06-22)Cardiovascular diseases (CVD) remain the major leading cause of death in the western world. Therefore, several approaches to achieve cardioprotection against any cardiovascular insult have been explored and to date, the ... -
Impact of Muscle Material Properties on the Hypertrophic Response of Aged Women to Resistance Exercise
(East Carolina University, 2016-07-21)All of the reports that comprise this dissertation center around the overarching hypothesis that the attenuated response to resistance exercise observed in older adults is caused by an impaired ability of the muscle to ... -
The Impact of Populating the Freshman Seminar on Retention, Student Perception of Content, Student Satisfaction and Connection to the Institution
(East Carolina University, 2008-11)The purpose of this study was to examine the relationship between how the freshman seminar course in extended orientation format is populated at a large research institution and its impact on student perception of content, ... -
THE IMPACT OF PRINCIPAL LEADERSHIP ON WORKING CONDITIONS AND TEACHER RETENTION IN NORTH CAROLINA MIDDLE SCHOOLS
(East Carolina University, 2009)Research indicates that administrative leadership is the most important factor in determining the climate of a school, and there are specific leadership attributes such as improving working conditions that promote retention. ... -
Impact of simulation experiences on learning transfer in new graduate registered nurses.
(East Carolina University, 2015)The purpose of this study was to evaluate the influence of pre-work factors (healthcare experience, type of education, type and frequency of simulation exposure) and work factors (type and frequency of simulation exposure) ... -
THE IMPACT OF STATE AND FEDERAL ACCOUNTABILITY STANDARDS UPON THE IMPLEMENTATION OF INCLUSION IN JOHNSTON COUNTY, NC HIGH SCHOOLS
(East Carolina University, 2012)As student accountability models have become the norm in the United States, first in individual states such as North Carolina and then throughout the nation with No Child Left Behind (NCLB), the implementation of inclusion ... -
IMPACT OF THE MULTI-CLASSROOM TEACHER MODEL IN ADDRESSING BEGINNING TEACHER SELF-EFFICACY AND RETENTION
(East Carolina University, 2021-04-20)A growing number of beginning teachers are leaving teaching within their first three years, with half leaving the profession in the first five years (Ingersoll, 2012; Stewart et al., 2021). In an attempt to slow this level ... -
THE IMPACT OF TUITION, PELL GRANTS, AND STATE APPROPRIATIONS ON COMMUNITY COLLEGE ENROLLMENT DURING CHALLENGING ECONOMIC TIMES
(East Carolina University, 2014)This study presents the results of a quantitative analysis of the headcount enrollment of 97 community colleges in North and South Carolina and Virginia during the period fall 2003 through fall 2012, a period that included ...