Browsing Dissertations by Title
Now showing items 532-551 of 1044
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The intracellular proteolytic fragment of CD44 alters CD44 function in chondrocytes
(East Carolina University, 2010)CD44 is an adhesion molecule involved in several biological functions and the primary receptor for hyaluronan (HA). In cartilage, CD44 participates in the interplay between cells and the extracellular matrix to fine tune ... -
INTRINSIC EXERCISE CAPACITY ON HIND LIMB ARTERIAL LIGATION: DIFFERENTIAL IMPACT OF ACTIVE EXERCISE AND ANDROGEN SIGNALING ON POST-ISCHEMIC RECOVERY
(East Carolina University, 2018-12-21)Peripheral arterial disease (PAD) is a common disease that is frequently caused by atherosclerosis and associated thrombosis, leading to a decrease in the blood supply to the lower extremities. PAD has various treatment ... -
INTRODUCING TRANSLANGUAGING PRACTICES IN AN INTERNATIONAL ELEMENTARY SCHOOL: THE CRITICAL ROLE OF INSTRUCTIONAL ASSISTANTS.
(East Carolina University, 2023-04-21)Language is the vehicle through which we express ourselves and interact with the people and places around us. Language shapes our identity within the varied communities in which we belong. Translanguaging is a concept that ... -
INVESTIGATING MECHANISMS REGULATING MAMMALIAN SPERMATOGONIAL DIFFERENTIATION AND MEIOTIC INITIATION
(East Carolina University, 2022-06-27)Spermatogonia differentiation and meiotic initiation are complex processes essential for male fertility. Despite knowing for nearly 60 years that retinoic acid (RA) is instrumental for successful production of functional ... -
INVESTIGATING MECHANISMS REGULATING MAMMALIAN SPERMATOGONIAL DIFFERENTIATION AND MEIOTIC INITIATION
(East Carolina University, 2022-06-27)Spermatogonia differentiation and meiotic initiation are complex processes essential for male fertility. Despite knowing for nearly 60 years that retinoic acid (RA) is instrumental for successful production of functional ... -
Investigating Non-Tight Junction Functions of Claudin-7: Regulating Large Intestine Stem Cell Functions and Niche Maintenance, and Junctional Protein Nanoarchitecture
(East Carolina University, 2022-12-12)Edit this abstract. -
Investigating the genetic basis of aposematic coloration in poison frogs
(East Carolina University, 2023-11-29)Aposematic organisms rely on their conspicuous appearance to signal that they are defended and unpalatable. Such phenotypes are strongly tied to survival and reproduction. Aposematic colors and patterns are highly variable; ... -
An Investigation of Auditory and Visual Temporal Processing in Children with Reading Disorders
(East Carolina University, 2009)Several lines of research have revealed a relationship between reading disorders (RD) and auditory temporal processing deficits. That is, subtle, yet rapid changes within an acoustic message are more difficult for individuals ... -
Investigation of the Anatomical and Physiological Changes Following the Use of a Pedicled Buccal Fat Pad Graft During Primary Palatoplasty
(East Carolina University, 2019-07-19)Children with cleft palate typically undergo primary surgery between 6-12 months of age to close the cleft in the palate and create proper muscle function for elevation and retraction of the velum for speech. About one ... -
Investigation of the Zinc binding region of Prothymosin-alpha : A spectroscopic and thermodynamic approach to study metal binding in Intrinsically disordered proteins
(East Carolina University, 2014)The goal of this study is to provide a deeper insight into how metals bind intrinsically disordered proteins (IDPs) by taking zinc binding to prothymosin-alpha as a case study. The involvement of metals in several diseases ... -
Investigations into the roles of bacteroides fragilis thioredoxins during the oxidative stress response
(East Carolina University, 2011)The Gram-negative Bacteroides fragilis is the most frequently isolated bacterium from anaerobic infections. Native to the human intestinal tract, it serves a symbiotic role breaking down complex polysaccharides and ... -
The involvement of cap-independent mRNA translation in cell fate decisions
(East Carolina University, 2014)During cell stress many biochemical processes are shut down. For example, global mRNA translation initiation is inhibited due to the disruption of the cap-dependent mRNA recruitment mechanism. One specific example of ... -
Ion Traffic Across Cellular Membranes
(East Carolina University, 2010)The cell membrane protects the delicate internal machinery of the cell and hosts a complex transport system for ion exchange with the environment. Energy is continually expended to maintain a transmembrane electrical ... -
The iron response regulator Irr controls iron homoeostasis in Brucella
(East Carolina University, 2014)Members of the genus Brucella are small, Gram-negative intracellular bacterial pathogens that are capable of infecting a wide range of mammalian hosts including humans. Brucella primarily reside inside of host macrophages. ... -
Is this Ship Covered?: The Intersection of Law, Geography, and Management of Sunken Military Craft
(East Carolina University, 2019-12-10)The legal framework protecting historic shipwrecks and other underwater cultural heritage in the United States is largely fragmented and not always effective. Factors that may influence the legal protection afforded a ... -
ISLANDS OF INNOVATION: EXAMINING THE NEXUS BETWEEN CULTURALLY RESPONSIVE RELATIONSHIPS AND COGNITIVELY DEMANDING ACADEMIC DISCOURSE
(East Carolina University, 2023-04-21)The purpose of the study was to examine the extent to which participants built meaningful culturally and linguistically responsive (CLR) relationships with students and to what extent those same participants engaged in ... -
Issues in Rural Pediatric Primary Care
(East Carolina University, 2013)Children in rural areas experience health disparities above and beyond their urban and suburban counterparts. In order to explore the needs of children and their families in rural health care settings, two research articles ... -
Jellyfish-human interactions in North Carolina
(East Carolina University, 2013)This dissertation investigated potential drivers of jellyfish-human interactions in North Carolina. Jellyfish populations and human use of coasts are increasing; therefore, jellyfish-human interactions are poised to become ... -
Job satisfaction and intent to leave of nursing assistants in a hospital setting.
(East Carolina University, 2015)Nursing assistants are an important part of the healthcare team in hospitals. However, there has been little research about the antecedents of job satisfaction and intent to leave of nursing assistants in hospitals. The ... -
JOYFUL LEARNING MATTERS: TEACHER PRACTICES IN AMPLIFYING JOYFUL LEARNING EXPERIENCES FOR CHINESE ENGLISH LANGUAGE LEARNERS
(East Carolina University, 2023-11-22)The purpose of this participatory action research project (PAR) was to study how a group of teachers designed and implemented strategies with the intent of amplifying joyful learning experiences for Chinese English Language ...