Browsing Dissertations by Title
Now showing items 541-560 of 1044
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Investigation of the Zinc binding region of Prothymosin-alpha : A spectroscopic and thermodynamic approach to study metal binding in Intrinsically disordered proteins
(East Carolina University, 2014)The goal of this study is to provide a deeper insight into how metals bind intrinsically disordered proteins (IDPs) by taking zinc binding to prothymosin-alpha as a case study. The involvement of metals in several diseases ... -
Investigations into the roles of bacteroides fragilis thioredoxins during the oxidative stress response
(East Carolina University, 2011)The Gram-negative Bacteroides fragilis is the most frequently isolated bacterium from anaerobic infections. Native to the human intestinal tract, it serves a symbiotic role breaking down complex polysaccharides and ... -
The involvement of cap-independent mRNA translation in cell fate decisions
(East Carolina University, 2014)During cell stress many biochemical processes are shut down. For example, global mRNA translation initiation is inhibited due to the disruption of the cap-dependent mRNA recruitment mechanism. One specific example of ... -
Ion Traffic Across Cellular Membranes
(East Carolina University, 2010)The cell membrane protects the delicate internal machinery of the cell and hosts a complex transport system for ion exchange with the environment. Energy is continually expended to maintain a transmembrane electrical ... -
The iron response regulator Irr controls iron homoeostasis in Brucella
(East Carolina University, 2014)Members of the genus Brucella are small, Gram-negative intracellular bacterial pathogens that are capable of infecting a wide range of mammalian hosts including humans. Brucella primarily reside inside of host macrophages. ... -
Is this Ship Covered?: The Intersection of Law, Geography, and Management of Sunken Military Craft
(East Carolina University, 2019-12-10)The legal framework protecting historic shipwrecks and other underwater cultural heritage in the United States is largely fragmented and not always effective. Factors that may influence the legal protection afforded a ... -
ISLANDS OF INNOVATION: EXAMINING THE NEXUS BETWEEN CULTURALLY RESPONSIVE RELATIONSHIPS AND COGNITIVELY DEMANDING ACADEMIC DISCOURSE
(East Carolina University, 2023-04-21)The purpose of the study was to examine the extent to which participants built meaningful culturally and linguistically responsive (CLR) relationships with students and to what extent those same participants engaged in ... -
Issues in Rural Pediatric Primary Care
(East Carolina University, 2013)Children in rural areas experience health disparities above and beyond their urban and suburban counterparts. In order to explore the needs of children and their families in rural health care settings, two research articles ... -
Jellyfish-human interactions in North Carolina
(East Carolina University, 2013)This dissertation investigated potential drivers of jellyfish-human interactions in North Carolina. Jellyfish populations and human use of coasts are increasing; therefore, jellyfish-human interactions are poised to become ... -
Job satisfaction and intent to leave of nursing assistants in a hospital setting.
(East Carolina University, 2015)Nursing assistants are an important part of the healthcare team in hospitals. However, there has been little research about the antecedents of job satisfaction and intent to leave of nursing assistants in hospitals. The ... -
JOYFUL LEARNING MATTERS: TEACHER PRACTICES IN AMPLIFYING JOYFUL LEARNING EXPERIENCES FOR CHINESE ENGLISH LANGUAGE LEARNERS
(East Carolina University, 2023-11-22)The purpose of this participatory action research project (PAR) was to study how a group of teachers designed and implemented strategies with the intent of amplifying joyful learning experiences for Chinese English Language ... -
Kapwa (Shared Identity): Filipino American Perspectives and Responses to Educational Leadership
(East Carolina University, 2023-04-21)Representing the makeup of educational leaders and social structure, the understanding and practice of educational leadership in the United States have centered on Western leadership perspectives. Even with the changing ... -
Keyboard layout in eye gaze communication access: typical vs. ALS
(East Carolina University, 2013)The purpose of the current investigation was to determine which of three keyboard layouts is the most efficient for typical as well as neurologically-compromised first-time users of eye gaze access. All participants (16 ... -
Kinin B1 Receptor Mediated Mechanisms in Hypertension
(East Carolina University, 2022-08-15)Hypertension continues to cause a burden on the global population as there are growing numbers of patients who present with treatment resistant hypertension. The etiology of hypertension is considered complex and multifactorial ... -
Kinin B1 Receptor Mediated Mechanisms in Hypertension
(East Carolina University, 2022-08-15)Hypertension continues to cause a burden on the global population as there are growing numbers of patients who present with treatment resistant hypertension. The etiology of hypertension is considered complex and multifactorial ... -
Knowledge of Sickle Cell Trait and Disease among African-American College Students
(East Carolina University, 2011)The term sickle cell disease (SCD) refers to a collection of hemoglobinopathies (inherited blood disorders) characterized by abnormal hemoglobin and produced through the homozygous inheritance of a sickle cell allele. ... -
LANGUAGE IS NOT MY HURDLE: IMPROVING EQUITABLE INSTRUCTIONAL PRACTICES ONE CLASSROOM AT A TIME
(East Carolina University, 2023-04-21)Language should not be a hurdle for English language learners in mathematics. The participatory action research study focused on how first-grade teachers identified, planned, and implemented discourse strategies to support ... -
LATINA IMMIGRANTS, HIV, AND THEIR EXPIERENCES WITH HEALTH CARE PROVIDERS IN THE U.S. AND THEIR HOME COUNTRY
(East Carolina University, 1/13/16)The intersection of factors associated with immigration in the Latina population and available culturally sensitive health care has not been well examined. There is a scarcity of research available that examines factors ... -
LATINO WOMEN’S EXPERIENCE OF SEXUAL VIOLENCE: A PHENOMENOLOGICAL STUDY
(East Carolina University, 2021-12-03)Sexual violence is a public health problem worldwide that disproportionately impacts women. The consequences for survivors are multiple in terms of their overall health (i.e., reproductive health effects, psychological ... -
Layered regulation of a pathway capable of altering quinolone production in Pseudomonas aeruginosa
(East Carolina University, 2014)Pseudomonas aeruginosa is a gram negative opportunistic pathogen which commonly infects hospitalized patients and those afflicted with cystic fibrosis. P. aeruginosa communicates intercellularly via a system of small ...