Browsing Dissertations by Title
Now showing items 581-600 of 1044
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m6A’s Unique and Dynamic Role in Breast Cancer Progression
(East Carolina University, 2023-07-18)Despite intense study, metastatic breast cancer is still the second leading cause of female death from cancer in the US. While many genetic lesions and environmental factors have been implicated in breast cancer progression, ... -
Macrophage Regulation in the Murine Inflammatory Response
(East Carolina University, 2018-08-30)The development of acute and chronic liver disease is a complex condition involving the dysregulation of hepatic metabolism and the accumulation of critical immune cells; specifically, the recruitment and activation of ... -
Managing for Self-Organization in a Changing World : Societal Responses to Shoreline Change
(East Carolina University, 2012)Catastrophic, episodic natural disasters such as hurricanes and earthquakes along with slower long-term natural processes such as erosion and sea level rise can have severe effects on the structure and function of human ... -
MANIPULATION OF FLOODING AND NUTRIENTS INFLUENCES PLANT-MICROBE INTERACTIONS AND WETLAND FUNCTION
(East Carolina University, 2020-06-22)The largest global stocks of organic carbon are in soils, where plants fix atmospheric carbon dioxide into biomass at higher rates than soil organic carbon is lost through decomposition and microbial respiration. Specifically, ... -
Massive open online courses and completion rates: does academic readiness and its factors influence completion rates in MOOCs?
(East Carolina University, 2016-12-06)With the increase in the cost of an education and the flat employment rate, many institutions and students are looking to online learning to solve this academic dilemma. Online education is thought to be a low-cost academic ... -
Massively multiplayer online role-playing games: problematic use
(East Carolina University, 2013)Massively Multiplayer Online Role Playing Games (MMORPGs) are a form of mass media with potential for behavioral addiction among some users. In past literature on internet addiction, MMORPG users have been included alongside ... -
Mast cells and the IL-33/ST2 axis are essential determinants of carbon nanotube toxicity
(East Carolina University, 2012)The rise of nanomaterial use in a variety of applications, including biomedical imaging and drug delivery, has led to concern about the potentially hazardous impacts on human health. Mast cells are critical for innate and ... -
MATERIALIZING MAKERSPACES: QUEERLY COMPOSING SPACE, TIME, AND (WHAT) MATTERS
(East Carolina University, 2017-07-19)This dissertation project explores makerspaces as non-traditional composing networks where makers work with (and against) unconventional digital and physical materials such as vinyl, cut paper, plastic filament, insects, ... -
Mathematical Modeling of Oxygen Transport, Cell Killing and Cell Decision Making in Photodynamic Therapy of Cancer
(East Carolina University, 2012)In this study we present a model of in vitro cell killing through type II Photodynamic Therapy (PDT) for simulation of the molecular interactions leading to cell death in time domain in the presence of oxygen transport ... -
MCLASS: READING 3D : AN ASSESSMENT OF THE IMPACT OF CONTINUOUS AND ONGOING PROFESSIONAL STAFF DEVELOPMENT
(East Carolina University, 2015-04-24)The purpose of this program evaluation was to explore the relationship that exists between the history of reading instruction, the impact of mClass: Reading 3D on student achievement in second grade, and the impact of ... -
Mclass: READING 3D— : UTILIZATION OF STUDENT DATA TO DETERMINE INSTRUCTIONAL PRACTICES
(East Carolina University, 2015-04-28)This dissertation is a program evaluation of a state-mandated early reading assessment program, titled mClass: Reading 3D, implemented in K–3 classrooms in a rural public school system in North Carolina. The purpose of ... -
Measured Resting Energy Expenditure Using a Fixed Function Indirect Calorimeter in the Clinical Setting as a Predictor of Success with Weight Change in an Obese Pediatric Population
(East Carolina University, 2010)The American Dietetic Association (ADA) standard of care for obese adults utilizes indirect calorimetry for calculating caloric targets for weight loss (1). Even though rates appear to be leveling off (2), childhood obesity ... -
MEASUREMENT OF WORD RETRIEVAL IN THE DISCOURSE OF PERSONS WITH APHASIA: STANDARD CORE LEXICON ITEM DEVELOPMENT AND PSYCHOMETRIC PROPERTIES
(East Carolina University, 8/5/2020)Core lexicon measures are a quantitative measure of lexical use in discourse for persons with aphasia. It is intended to provide clinicians with a clinician-friendly means to quantify lexical use in discourse based on ... -
MEASURING PROGRAM EFFECTIVENESS : ASSESSMENT AND ACCOUNTABILITY IN A TWO-WAY IMMERSION PROGRAM
(East Carolina University, 2014)School districts across the country are implementing bilingual education models such as two-way immersion, also known as dual language programs. The goals of two-way immersion programs are to assist students to obtain high ... -
Measuring the Ecosystem Impacts of Commercial Shrimp Trawling and Other Fishing Gear in Core Sound, North Carolina Using Ecological Network Analysis
(East Carolina University, 2012)The impacts of commercial trawling are well documented, especially alteration of benthic environments, removal of targeted and by-catch species, and alteration of food webs. I investigated and modeled the impacts of shrimp ... -
Mechanisms for central cannabinoid receptor 1 evoked sympathoexcitation/pressor response in conscious rats
(East Carolina University, 2010)The main goal of the current study was to elucidate the molecular mechanisms implicated in central cannabinoid receptor 1 (CB1R)-evoked sympathoexcitation/pressor response. In pursuit of this goal, the candidate first ... -
MECHANISMS OF LEFT VENTRICULAR REMODELING IN PHYSIOLOGICAL AND PATHOLOGICAL CONDITIONS
(East Carolina University, 8/5/2020)Cardiac remodeling is composed of molecular, cellular, and interstitial changes in the cardiac tissue that affect the size, shape, and function of the heart. There are two types of cardiac remodeling: physiological and ... -
Mechanistic Strategies of Two-component Flavin-dependent Monooxygenases Involved in Sulfur Acquisition
(East Carolina University, 2023-08-09)All organisms require sulfur for diverse metabolic and physiological processes. Unlike mammals, bacteria are often deprived of sulfur in their natural habitat. To meet their sulfur needs, bacteria express various proteins ... -
Medical Family Therapy : Conceptual Clarification and Consensus for an Emerging Profession
(East Carolina University, 2010)The term Medical Family Therapy (MedFT) was coined in the early 1990s (McDaniel, Hepworth, & Doherty, 1992a) by a team of family therapists and a family psychologist. Since then there has been growing interest in MedFT, ... -
MEDICAL FAMILY THERAPY IN A PRIMARY CARE SETTING : A MODEL OF INTEGRATION
(East Carolina University, 2011)As the profession of marriage and family therapy (MFT), as well as the emerging sub-discipline of medical family therapy (MedFT), continue to grow and evolve within the current mental health care system, the arena of primary ...