Browsing Dissertations by Title
Now showing items 153-172 of 284
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Managing for Self-Organization in a Changing World : Societal Responses to Shoreline Change
(East Carolina University, 2012)Catastrophic, episodic natural disasters such as hurricanes and earthquakes along with slower long-term natural processes such as erosion and sea level rise can have severe effects on the structure and function of human ... -
Massively multiplayer online role-playing games: problematic use
(East Carolina University, 2013)Massively Multiplayer Online Role Playing Games (MMORPGs) are a form of mass media with potential for behavioral addiction among some users. In past literature on internet addiction, MMORPG users have been included alongside ... -
Mast cells and the IL-33/ST2 axis are essential determinants of carbon nanotube toxicity
(East Carolina University, 2012)The rise of nanomaterial use in a variety of applications, including biomedical imaging and drug delivery, has led to concern about the potentially hazardous impacts on human health. Mast cells are critical for innate and ... -
Mathematical Modeling of Oxygen Transport, Cell Killing and Cell Decision Making in Photodynamic Therapy of Cancer
(East Carolina University, 2012)In this study we present a model of in vitro cell killing through type II Photodynamic Therapy (PDT) for simulation of the molecular interactions leading to cell death in time domain in the presence of oxygen transport ... -
Measured Resting Energy Expenditure Using a Fixed Function Indirect Calorimeter in the Clinical Setting as a Predictor of Success with Weight Change in an Obese Pediatric Population
(East Carolina University, 2010)The American Dietetic Association (ADA) standard of care for obese adults utilizes indirect calorimetry for calculating caloric targets for weight loss (1). Even though rates appear to be leveling off (2), childhood obesity ... -
MEASURING PROGRAM EFFECTIVENESS : ASSESSMENT AND ACCOUNTABILITY IN A TWO-WAY IMMERSION PROGRAM
(East Carolina University, 2014)School districts across the country are implementing bilingual education models such as two-way immersion, also known as dual language programs. The goals of two-way immersion programs are to assist students to obtain high ... -
Measuring the Ecosystem Impacts of Commercial Shrimp Trawling and Other Fishing Gear in Core Sound, North Carolina Using Ecological Network Analysis
(East Carolina University, 2012)The impacts of commercial trawling are well documented, especially alteration of benthic environments, removal of targeted and by-catch species, and alteration of food webs. I investigated and modeled the impacts of shrimp ... -
Mechanisms for central cannabinoid receptor 1 evoked sympathoexcitation/pressor response in conscious rats
(East Carolina University, 2010)The main goal of the current study was to elucidate the molecular mechanisms implicated in central cannabinoid receptor 1 (CB1R)-evoked sympathoexcitation/pressor response. In pursuit of this goal, the candidate first ... -
Medical Family Therapy : Conceptual Clarification and Consensus for an Emerging Profession
(East Carolina University, 2010)The term Medical Family Therapy (MedFT) was coined in the early 1990s (McDaniel, Hepworth, & Doherty, 1992a) by a team of family therapists and a family psychologist. Since then there has been growing interest in MedFT, ... -
MEDICAL FAMILY THERAPY IN A PRIMARY CARE SETTING : A MODEL OF INTEGRATION
(East Carolina University, 2011)As the profession of marriage and family therapy (MFT), as well as the emerging sub-discipline of medical family therapy (MedFT), continue to grow and evolve within the current mental health care system, the arena of primary ... -
Medical Family Therapy Meets Childhood Obesity
(East Carolina University, 2010)The dissertation is a compilation of two journal articles. The first article is a literature review that addresses integrated care for childhood obesity with consideration for clinical, operational, and financial practices. ... -
A META-ANALYSIS OF RESEARCH ON THE MEDIATED EFFECTS OF PRINCIPAL LEADERSHIP ON STUDENT ACHIEVEMENT : EXAMINING THE EFFECT SIZE OF SCHOOL CULTURE ON STUDENT ACHIEVEMENT AS AN INDICATOR OF TEACHER EFFECTIVENESS
(East Carolina University, 2009)The leadership of the school principal has long been associated with teacher effectiveness and student achievement. Research on the topic of principal leadership supports this association (Hallinger, Bickman, & Davis, 1996; ... -
Metabolic Inflexibility in Response to Lipid Oversupply with Obesity: Epigenetic Modifications Play a Role
(East Carolina University, 2013)The ability to adjust substrate oxidation according to nutrient availability has been termed `metabolic flexibility' and is a critical factor in overall metabolic health. In respect to fatty acid oxidation (FAO) metabolic ... -
Metabolic Inflexibility in Skeletal Muscle With Obesity
(East Carolina University, 2009)The skeletal muscle of obese individuals has a reduced capacity to oxidize lipids. The hypothesis to be tested in this dissertation is that the ability to regulate lipid oxidation in response to lipid exposure is impaired ... -
Modulation of IKKβ with AMPK Improves Insulin Sensitivity in Skeletal Muscle
(East Carolina University, 2008-11)Activation of the insulin receptor substrate (IRS)-1 is necessary for proper transduction of the insulin signal. IRS-1 serine312(human)/307(rodent) phosphorylation, however, results in disruption of this signal and subsequent ... -
Molecular Mechanisms of Peripheral N-Methyl-D-Aspartate Mediated Pressor Response
(East Carolina University, 2012)The primary goal of this study was to characterize the N-Methyl-D-Aspartate (NMDA) receptor within the cardiovascular system and elucidate the molecular mechanisms involved in peripheral NMDA receptor-mediated pressor ... -
Molecular mechanisms of TMEFF2 action in Prostate Cancer
(East Carolina University, 2013)The transmembrane protein with epidermal growth factor and two follistatin motifs 2 (TMEFF2) is an evolutionarily conserved type I transmembrane protein expressed in the embryo and limited adult tissues, mainly the brain ... -
Multifunctional experimental assessment in a newly established Mediterranean restored marsh : marsh elevation, carbon accumulation and pollutant concentration reduction
(East Carolina University, 2014)The Delta of the Ebro River (Catalonia, Spain) is among the most important marsh areas in the Western Mediterranean Sea, highly valuable both economically and ecologically. Fluvial sediment reduction by dams in a relative ... -
Multiple Factors Influence the Strength of Intraguild Interactions
(East Carolina University, 2011)Species engaged in intraguild predation (IGP) not only compete for the same food resources but can also eat each other. In some cases, a predator species in a higher trophic position (i.e., a top predator) can eat a ... -
Multiple Translation Factor eIF4G (IFG-1) Isoforms are Required for the Apoptosome-Dependent Activation of Germ Cell Apoptosis
(East Carolina University, 2010)Apoptosis is a naturally occurring process during animal development required for the programmed killing and removal of injured cells. Cellular insult induces a switch in translation that allows for the rapid synthesis ...