Browsing Dissertations by Issue Date
Now showing items 21-40 of 1044
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Metabolic Inflexibility in Skeletal Muscle With Obesity
(East Carolina University, 2009)The skeletal muscle of obese individuals has a reduced capacity to oxidize lipids. The hypothesis to be tested in this dissertation is that the ability to regulate lipid oxidation in response to lipid exposure is impaired ... -
Functional Aging of the Inner Ear Sensory Systems in Mouse Models of Age-Related Hearing Loss
(East Carolina University, 2009)Age related structural and functional change in the cochlea have been well described and predisposing factors including genetic background, gender, and environmental factors have been identified. To date, nine genetic loci ... -
Pain Management after Cardiac Surgery
(East Carolina University, 2009)Postoperative pain relief is one of the most important concerns for patients undergoing cardiac surgery and is one of the most clinically challenging problems for nurses. It is widely recognized that postoperative pain can ... -
THE ROLE OF RACE AND GENDER IN THE MENTORING EXPERIENCES AND CAREER SUCCESS OF AFRICAN AMERICAN FEMALE SENIOR EXECUTIVE ADMINISTRATORS IN HIGHER EDUCATION
(East Carolina University, 2009)From 1995 to 2005 education doctoral degrees conferred to African American females increased by 92%, however the increase in availability among this population for higher education administrator positions has not kept pace ... -
CURRICULAR JOINT VENTURE : A MODEL FOR MEETING COMMUNITY AND EDUCATIONAL DEMANDS
(East Carolina University, 2009)The purpose of this study was to describe the inception, development, and implementation of a unique curricular joint venture, the University of North Carolina at Chapel Hill (UNC-Chapel Hill)/Elizabeth City State University ... -
A META-ANALYSIS OF RESEARCH ON THE MEDIATED EFFECTS OF PRINCIPAL LEADERSHIP ON STUDENT ACHIEVEMENT : EXAMINING THE EFFECT SIZE OF SCHOOL CULTURE ON STUDENT ACHIEVEMENT AS AN INDICATOR OF TEACHER EFFECTIVENESS
(East Carolina University, 2009)The leadership of the school principal has long been associated with teacher effectiveness and student achievement. Research on the topic of principal leadership supports this association (Hallinger, Bickman, & Davis, 1996; ... -
Affluence and Influence : A Study of Inequities in the Age of Excellence
(East Carolina University, 2009)This study analyzed the impact of school poverty levels on variances in elementary math achievement and preparation-based teacher effects. The research was conducted using data from the Gaston County School District, the ... -
TEACHER PREPARATION COST STUDY : A COMPARATIVE ANALYSIS OF UNC SYSTEM-LEVEL FINANCIAL INPUTS AGAINST CAMPUS-LEVEL PRODUCTIVITY OUTPUTS
(East Carolina University, 2009)The University of North Carolina General Administration has required all constituent institutions with teacher education programs to expand their productivity goals to meet the state's teacher workforce needs. This study ... -
Controls on Septic System Wastewater Treatment and Shallow Groundwater Quality in Coastal North Carolina
(East Carolina University, 2009)Excess nitrogen and bacteria concentrations in coastal waters of North Carolina have led to eutrophic conditions, fish kills, and the closure of shellfish waters. Regulatory efforts by the state to reduce nitrogen and ... -
An Investigation of Auditory and Visual Temporal Processing in Children with Reading Disorders
(East Carolina University, 2009)Several lines of research have revealed a relationship between reading disorders (RD) and auditory temporal processing deficits. That is, subtle, yet rapid changes within an acoustic message are more difficult for individuals ... -
The role of peroxisome proliferator-activated receptor-gamma in surfactant catabolism in the alveolar macrophage
(East Carolina University, 2009)Pulmonary alveolar proteinosis (PAP) is a lung disease characterized by surfactant accumulation in the alveolar spaces and alveolar macrophages. Although PAP is rare, surfactant abnormalities occur in many lung diseases ... -
Responses of dominant marsh macrophytes to inundation and disturbance and assessing marsh ecosystem services
(East Carolina University, 2009)Within two hydrodynamically different inundation regimes in North Carolina, the growth response and interactions of two dominant marsh macrophytes were evaluated over a range of inundation periods to understand better how ... -
Enforced expression of HoxA9 in b-lineage all promotes survival and proliferation of leukemic cells
(East Carolina University, 2009)HoxA9 is frequently overexpressed in acute myeloid leukemia, myelodysplastic syndrome and a subset of acute lymphoblastic leukemia. In mouse models, HoxA9 has been shown to promote leukemogenesis. In spite of a seemingly ... -
Interaction of memantine with ethanol consumption and dopaminergic function in high ethanol preferring rats
(East Carolina University, 2009)N-methyl-D-aspartate (NMDA) receptor antagonists have been reported to decrease ethanol consumption in rodents, but these drugs often produce adverse side effects. Memantine is a neuroprotective and low-affinity, ... -
The unique roles of IFE-1, a germline-specific isoform of eukaryotic translation factor 4E, during gametogenesis
(East Carolina University, 2009)Fertility and embryonic viability are measures of efficient germ cell growth and differentiation. During oogenesis, spermatogenesis and embryogenesis cells initially proliferate then differentiate into specific tissues. ... -
The Biochemical Characterization Of Neuronal K+ Channel N-Glycans And Their Role In Regulating K+ Channel Function
(East Carolina University, 2009)The Kv3 and Kv1 subfamilies of voltage–gated K+ channels are critical components which contribute to action potential repolarization throughout the central nervous system. Here, it was shown that both absolutely conserved ... -
The Role of Axl and Axl-like Proteins in Murine Spermatogenesis
(East Carolina University, 2009)Mice lacking the Axl receptor tyrosine kinase (RTK) and its family members exhibit detrimental effects on their reproductive ability. AXL is localized to Sertoli cells, which are the major nurturing cells in the seminiferous ... -
The Distribution Of Regulated Actomyosin States Is Central To Cardiac Muscle Regulation And Disturbance Of This Distribution Leads To Congenital Cardiomyopathies
(East Carolina University, 2009)Hypertrophic and restrictive cardiomyopathies are congenital cardiac diseases that have an incidence of over one in five hundred and may lead to sudden cardiac death. One of the main impediments to directed treatment is ... -
Oxytocin Modulation of Zebra Finch Vocal Development
(East Carolina University, 2010)Autism spectrum disorder is associated with deficits in three main behavioral areas: social behaviors, repetitive behaviors, and language abnormalities. Accumulating evidence suggests a potential role for oxytocin signaling ... -
Role of nicotinic acetylcholine receptor subtypes α4β2 and α7 in nicotine-ethanol interaction and cross-tolerance: functional correlation with cerebellar nitric oxide
(East Carolina University, 2010)The prevalent co-abuse of alcohol and tobacco products results in higher morbidity and mortality rates than those caused by either drug alone, thus posing a serious health problem. Understanding the interactive relationship ...