Browsing Dissertations by Author "Abdel-Rahman, Abdel A."
-
Central GPR109A Mediates Neuronal Oxidative Stress and Pressor Response in Conscious Rats
Rezq, Samar (East Carolina University, 2016-05-03)The primary goal of this study was to characterize the role of GPR109A in the rostral ventrolateral medulla (RVLM) in blood pressure (BP) regulation and to elucidate the mechanisms involved in the hypertensive response ... -
Disrupted Adiponectin-Connexin43 Signaling Underlies Exacerbated Myocardial Dysfunction in Diabetic Female Rats
Leffler, Korin Eileen (East Carolina University, 2019-04-25)The 2015 American Heart Association scientific statement has advocated for sex- specific research to understand the paradoxically higher sensitivity of women to type 2 diabetes mellitus (T2DM)-associated cardiovascular ... -
Kinin B1 Receptor Mediated Mechanisms in Hypertension
Parekh, Rohan U (East Carolina University, 2022-08-15)Hypertension continues to cause a burden on the global population as there are growing numbers of patients who present with treatment resistant hypertension. The etiology of hypertension is considered complex and multifactorial ... -
Mechanisms for central cannabinoid receptor 1 evoked sympathoexcitation/pressor response in conscious rats
Ibrahim, Badr Mostafa Sadek (East Carolina University, 2010)The main goal of the current study was to elucidate the molecular mechanisms implicated in central cannabinoid receptor 1 (CB1R)-evoked sympathoexcitation/pressor response. In pursuit of this goal, the candidate first ... -
Molecular Mechanisms of Peripheral N-Methyl-D-Aspartate Mediated Pressor Response
McGee, Marie (East Carolina University, 2012)The primary goal of this study was to characterize the N-Methyl-D-Aspartate (NMDA) receptor within the cardiovascular system and elucidate the molecular mechanisms involved in peripheral NMDA receptor-mediated pressor ... -
Role of central cannabinoid receptor GPR18 in cardiovascular regulation
Penumarti, Anusha (East Carolina University, 2014)The primary goal of this study was to characterize the role of GPR18 in the rostral ventrolateral medulla (RVLM) in blood pressure (BP) regulation and elucidate the mechanisms involved in central GPR18 mediated hypotensive ...