Browsing Dissertations by Subject "Oncology"

Now showing items 1-7 of 7

  • Adolescent and Young Adult Oncology Patients and their Caregivers 

    Kolobova, Irina (East Carolina University, 2016-05-03)
    Nearly 70,000 adolescents and young adults (AYA; ages 15-39) are diagnosed with cancer each year. Despite AYAs being identified in the late 1990s as a biopsychosocially distinct population from children and adults, they ...

  • COMPARATIVE ANALYSIS OF TWO HUMAN CANCER CELL LINES FOLLOWING EXPOSURE TO LOW DOSE RADIATION 

    Nangami, Gladys N. (East Carolina University, 2011)
    Over the past two decades, studies on the cellular response to very low dose radiation have been revolutionizing historically-held paradigms of cellular radioresponse. Indeed, a host of seemingly contradictory events have ...

  • Functions of claudin-7 in human lung cancer 

    Lu, Zhe (East Carolina University, 2012)
    Lung cancer is the second most common cancer and the most common cause of cancer-related death in both men and women in the United States with a very poor overall 5-year survival rate. Nearly 95% of the lung cancer originates ...

  • Molecular mechanism of anandamide-induced apoptosis in non-melanoma skin cancer. 

    Soliman, Eman (East Carolina University, 2015)
    Non-melanoma skin cancer (NMSC) is the most common cancer in the United States. The absence of selective toxicity is the major problem associated with chemotherapeutic and radiation therapy for NMSCs. The goal of the present ...

  • Molecular mechanisms of TMEFF2 action in Prostate Cancer 

    Chen, Xiaofei (East Carolina University, 2013)
    The transmembrane protein with epidermal growth factor and two follistatin motifs 2 (TMEFF2) is an evolutionarily conserved type I transmembrane protein expressed in the embryo and limited adult tissues, mainly the brain ...

  • p53 and NGAL: dual regulatory roles in advanced prostate cancer 

    Chappell, William H. (East Carolina University, 2011)
    The development of prostate cancer from small regions of hyperplasia to invasive tumors requires genetic and epigenetic alterations of critical cellular components to aid in the development of cells more adapted for aberrant ...

  • Synthesis, structure, photophysics, and biological activity of platinum (II) complexes 

    Vezzu, Dileep Atchyuth Kumar (East Carolina University, 2013)
    The synthesis, structure, and photophysical properties of luminescent platinum (II) complexes with different coordination patterns, (C^C*N^N), (N^C*N), (N^N*C) and (N^N^C) are reported, where "C^N or N^N" denotes a bidentate ...