Browsing Dissertations by Subject "Synapses"
Now showing items 1-2 of 2
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The Endocannabinoid System Regulates Synaptogenesis in a Cortical Spheroid Model of Fetal Neurodevelopment
(East Carolina University, 2021-07-20)The endocannabinoid system plays a complex role in synaptogenesis and the subsequent development of neural circuitry during fetal brain development. The cannabinoid receptor type 1 controls synaptic strength at both ... -
THE HYALURONAN EXTRACELLULAR MATRIX CRITICALLY REGULATES SYNAPSE FORMATION IN DEVELOPING NEURAL NETWORKS
(East Carolina University, 2021-04-21)The majority of neurodevelopmental disorders present with an imbalance in synaptic signal transmission. The delicate balance of excitatory to inhibitory synaptic transmission is regulated by multiple extracellular and ...