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Power and Place : A Case Study Approach to Rethinking Crisis Communication
(East Carolina University, 2010)
This dissertation examines a 2003 explosion at a pharmaceutical plant in Kinston, North Carolina against the framework of both crisis communication theory and critical discourse analysis theory. In the wake of the explosion, ...
Discovery and investigation of a novel role for mitochondrial prohibitin in mitigating acute heart failure in endotoxic shock
(East Carolina University, 2014)
Sepsis results in more than 200,000 deaths annually and is the 10th leading cause of death in the United States (US). In spite of significant advances in medical care the mortality rate for sepsis has continued to rise. ...
Human-Environment Interaction and Water Complexities : Mustering Science and Policy for a Coastal Resources Management Approach to Counterinsurgency (COIN) Operations
(East Carolina University, 2012)
Managing coastal resources is challenging in the best of circumstances. Bringing science and policy together to manage coastal resources effectively for the purpose of orchestrating population-centric counterinsurgency ...
The therapeutic potential of Rho GTPase intervention
(East Carolina University, 2013)
Small GTPases of the Rho family are well established regulators of critical cellular functions including cytoskeletal remodeling, motility, vesicle trafficking and cell cycle control. Additionally, aberrant signaling ...
Are Marine Migrations of Striped Bass Genetically Pre-determined? : An investigation of Albemarle Sound-Roanoke River Striped Bass Migratory Patterns
(East Carolina University, 2010)
Striped bass, Morone saxatilis, is one of the most thoroughly studied anadromous fish species in the United States, with records governing the management of the species dating back to the late 1600s. However, management ...
Correlating the Morphological and Light Scattering Properties of Biological Cells
(East Carolina University, 2013)
The scattered light pattern from a biological cell is greatly influenced by the internal structure and optical properties of the cell. This research project examines the relationships between the morphological and scattering ...
Recruitment of Estuarine-Dependent Alosines to Roanoke River and Albemarle Sound, North Carolina
(East Carolina University, 2012)
The deleterious effects of dams on alosine populations are widely documented in many rivers along the Atlantic coast. Alterations to the natural hydrologic regime can disrupt spawning, egg dispersal, and recruitment of ...
Resilience differences of Black Greek-Lettered Organization members and African-American students at Predominantly White Institutions
(East Carolina University, 2013)
Even though the number of African American students has increased on college campuses, particularly Predominately White Institutions (PWIs), over the last century, they are less likely to graduate than their White counterparts ...
Fesselin and caldesmon: natively unfolded proteins in smooth muscle regulation
(East Carolina University, 2010)
Dysregulation of smooth muscle contraction is linked to diseases such as atherosclerosis, asthma, hypertension, urinary incontinence, premature birth and others. The goal of this project is to contribute to our understanding ...
THE ROLE OF SDF-1[alpha] AS A VASCULOGENIC CHEMOKINE AND ENDOTHELIUM-ASSOCIATED CELL ADHESION MOLECULE FOR THE RECRUITMENT OF BONE MARROW-DERIVED PROGENITOR CELLS TO DEVELOPING TUMORS
(East Carolina University, 2010)
Tumor vascularization is an important control point in cancer progression and its inhibition is a promising approach to cancer therapy. Stromal-derived factor-1 alpha (SDF-1 alpha or CXCL12) is a chemoattractant for ...