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Fish oil disrupts B cell plasma membrane lateral organization and immunological synapse formation
(East Carolina University, 2012)
Fish oil has immunosuppressive properties that could provide treatment for numerous inflammatory and autoimmune disorders. The primary bioactive components of fish oil, which are the n-3 polyunsaturated fatty acids (PUFAs) ...
An examination of the functional role of TMEFF2 in prostate cancer and the translational regulatory mechanisms controlling its expression
(East Carolina University, 2012)
Prostate cancer is the most commonly diagnosed cancer in American men and accounts for approximately 11% of cancer-related deaths. Although promising treatment strategies have been developed and are currently being tested ...
Arctic Coastal Lagoons of Cape Krusenstern National Monument : Subsistence, Ecosystem Characterization, and Management
(East Carolina University, 2012)
The main objective of this research was to provide baseline water quality and species data for the five coastal lagoons in Cape Krusenstern National Monument (CAKR). Coastal lagoons are habitat for fish species that are ...
Influence of carbon nanomaterial exposure on pro-constrictor mechanisms during pregnancy
(East Carolina University, 2013)
Engineered carbon based nanoparticles (CNP) such as fullerenes and multiwalled carbon nanotubes (MWCNTs) are increasingly used in industries and in nanomedicine as a platform for drug delivery. Following environmental/o ...
p53 and NGAL: dual regulatory roles in advanced prostate cancer
(East Carolina University, 2011)
The development of prostate cancer from small regions of hyperplasia to invasive tumors requires genetic and epigenetic alterations of critical cellular components to aid in the development of cells more adapted for aberrant ...
Inhibition of Stuttering from Second Speech Signals: An Evaluation of Temporal and Hierarchical Aspects
(East Carolina University, 2012)
Stuttering is an intermittent and involuntary speech disorder overtly characterized by syllable repetitions, phoneme prolongations and postural fixations that disrupt the natural flow of speech. Overt stuttering is reduced ...
Healthcare Providers' Experiences with Screening for Intimate Partner Violence Among Migrant and Seasonal Farmworking Women : A Phenomenological Study
(East Carolina University, 2014)
Migrant and seasonal farmworking (MSFW) women experience greater levels of intimate partner violence (IPV) and have lower awareness of available resources than the general population. Although healthcare providers have ...
Shifting the Atmosphere : An Examination of the Relationships among African-American Female Discourse(s), Culturally Competent Education, and Social Action through the Black Church against Domestic Violence
(East Carolina University, 2013)
This dissertation explores the relationship(s) between rural African-American women's discourses and social advocacy/action against the social ill of domestic violence in order to provide insights into existing knowledge ...
Mechanisms for central cannabinoid receptor 1 evoked sympathoexcitation/pressor response in conscious rats
(East Carolina University, 2010)
The main goal of the current study was to elucidate the molecular mechanisms implicated in central cannabinoid receptor 1 (CB1R)-evoked sympathoexcitation/pressor response. In pursuit of this goal, the candidate first ...
The Impact of a Vocational Counseling Based Substance Abuse Intensive Outpatient Program upon Work and Well-Being: A Pilot Study
(East Carolina University, 2011)
Even though recovery from Substance Use Disorders (SUDs) involves changes among a number of life domains, services have traditionally focused on abstinence from substances. Cursory attention is placed on holistic treatment ...