Search
Now showing items 231-240 of 245
RESTORATIVE JUSTICE: IMPLEMENTING SUSTAINABLE RESTORATIVE PRACTICES IN A K-12 SCHOOL
(East Carolina University, 2022-08-19)
The purpose of this research is to describe how sustainable restorative practices focused on the intention of using inclusive school leadership, curriculum, wrap around supports, transformative community engagement, high ...
Skeletal Muscle Purine Nucleotide Degradation and Atrophy: Cause or Consequence of Increased Uric Acid Production
(East Carolina University, 2022-07-26)
Elevated serum uric acid is a risk factor for mortality in diseases and critical illnesses associated with skeletal muscle atrophy. Uric acid is generated by xanthine oxidoreductase (XOR) and XOR inhibitors can partially ...
Examining the therapeutic potential of the investigational agent, 15dPMJ2, in mismatch repair proficient colon cancer
(East Carolina University, 2022-08-15)
Despite the success of immune checkpoint inhibitor (ICI) therapy in many cancers, colon cancer with low microsatellite instability (MSI-L), also known as proficient mismatch repair (pMMR), does not respond to these agents. ...
INVESTIGATING MECHANISMS REGULATING MAMMALIAN SPERMATOGONIAL DIFFERENTIATION AND MEIOTIC INITIATION
(East Carolina University, 2022-06-27)
Spermatogonia differentiation and meiotic initiation are complex processes essential for male fertility. Despite knowing for nearly 60 years that retinoic acid (RA) is instrumental for successful production of functional ...
Counselors’ Attitudes Toward Sex Trafficking: A Quantitative, National Analysis
(East Carolina University, 2022-06-03)
For more than 20 years, the pervasive problem of sex trafficking has garnered increasing attention in research, advocacy, and legislation. The cumulative research focuses on the trafficking of women and girls based on the ...
THE EFFECT OF SOCIAL EXPERIENCE ON THE SYNERGISTIC NEUROMODULATION OF MOTOR CIRCUITS
(East Carolina University, 2022-07-15)
Forming social groups is a critical adaptive strategy for the survival of many animal species, where conflict between members can result in dominance relationships. Dominance relationships are often formed through aggressive ...
Characterization of the glucose transport mechanism responsible for mechanical overload- and acute injury-stimulated skeletal muscle glucose uptake
(East Carolina University, 2022-06-24)
Skeletal muscle is a highly adaptable tissue. In response to stimuli such as resistance exercise training or trauma/injury, muscle glucose uptake is stimulated to fuel the energetic and biosynthetic demands of growth, ...
Lèvy noise induced steady states
(East Carolina University, 2022-06-08)
Systems far from equilibrium organize themselves to accommodate energy throughput. It is also in these nonequilibrium systems where noise has often been found to follow alpha-stable distributions, commonly called Lèvy ...
Cultural Heritage and Coastal Resiliency: An Assessment of Archaeological Sites in North Carolina
(East Carolina University, 2022-07-19)
Climate change is impacting archaeological sites on North Carolina’s coast. Sea-level rise and landscape inundation are often emphasized as the primary threat to cultural heritage from climate change; erosion is identified ...
The Effects of Bullying on Mental Health in Adolescents with Neurological Conditions
(East Carolina University, 2022-07-15)
Approximately one out of five children experience bullying at some point throughout their educational career. Students who experience bullying are at increased risk for social problems, sleep difficulties, anxiety, and ...