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The effects of reading acceleration on reading comprehension and decoding accuracy in high school students with reading disorders.
(East Carolina University, 2012)
Reading disorders have been hypothesized to result from an asynchrony between speed of processing characteristics of auditory and visual systems involved in decoding. It is hypothesized that reading at faster rates can ...
Mast cells and the IL-33/ST2 axis are essential determinants of carbon nanotube toxicity
(East Carolina University, 2012)
The rise of nanomaterial use in a variety of applications, including biomedical imaging and drug delivery, has led to concern about the potentially hazardous impacts on human health. Mast cells are critical for innate and ...
The bhuTUV and bhuO genes play vital roles in the ability of Brucella abortus to use heme as an iron source and are regulated in an iron-responsive manner by RirA and Irr
(East Carolina University, 2012)
Brucella abortus is a Gram negative intracellular pathogen that causes the zoonotic disease brucellosis. Antibiotic treatment for brucellosis in humans is prolonged and sometimes followed by relapses. Currently, the United ...
Decolonizing Education : A Critical Discourse Analysis of Post-Secondary Humanities Textbooks
(East Carolina University, 2012)
This dissertation examines nine post-secondary humanities textbooks published between 2001 and 2011 using an approach that includes both qualitative and quantitative methodology to analyze the written and visual content ...
Measuring the Ecosystem Impacts of Commercial Shrimp Trawling and Other Fishing Gear in Core Sound, North Carolina Using Ecological Network Analysis
(East Carolina University, 2012)
The impacts of commercial trawling are well documented, especially alteration of benthic environments, removal of targeted and by-catch species, and alteration of food webs. I investigated and modeled the impacts of shrimp ...
Elucidating the Mechanism of Action of Unnatural Amino Acid Containing Antimicrobial Peptides in Membrane Environments
(East Carolina University, 2012)
Organism resistance continues to develop to the currently available antimicrobial compounds necessitating the development of innovative new therapeutic compounds with different specificities and mechanisms of action that ...
NADPH Oxidase as a Mechanistic Link Between Erectile Dysfunction, Peripheral, and Coronary Endothelial Dysfunction in Obesity
(East Carolina University, 2012)
Cardiovascular complications involving both microvascular and macrovascular tissues are the major cause of morbidity and mortality in obese patients. Clinical and epidemiological studies suggest that erectile dysfunction ...
Narrative, Identity, and Sense of Place Discourse : Woman's Club of Fayetteville, North Carolina, 1906-1912
(East Carolina University, 2012)
This dissertation analyzes the discourse (the narratives) used by members of the Woman's Club of Fayetteville in Fayetteville, North Carolina, from 1906 through 1912, as they (1) saved the Market House from destruction and ...
Molecular Mechanisms of Peripheral N-Methyl-D-Aspartate Mediated Pressor Response
(East Carolina University, 2012)
The primary goal of this study was to characterize the N-Methyl-D-Aspartate (NMDA) receptor within the cardiovascular system and elucidate the molecular mechanisms involved in peripheral NMDA receptor-mediated pressor ...
Functions of claudin-7 in human lung cancer
(East Carolina University, 2012)
Lung cancer is the second most common cancer and the most common cause of cancer-related death in both men and women in the United States with a very poor overall 5-year survival rate. Nearly 95% of the lung cancer originates ...