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Fish oil disrupts B cell plasma membrane lateral organization and immunological synapse formation
(East Carolina University, 2012)
Fish oil has immunosuppressive properties that could provide treatment for numerous inflammatory and autoimmune disorders. The primary bioactive components of fish oil, which are the n-3 polyunsaturated fatty acids (PUFAs) ...
An examination of the functional role of TMEFF2 in prostate cancer and the translational regulatory mechanisms controlling its expression
(East Carolina University, 2012)
Prostate cancer is the most commonly diagnosed cancer in American men and accounts for approximately 11% of cancer-related deaths. Although promising treatment strategies have been developed and are currently being tested ...
Arctic Coastal Lagoons of Cape Krusenstern National Monument : Subsistence, Ecosystem Characterization, and Management
(East Carolina University, 2012)
The main objective of this research was to provide baseline water quality and species data for the five coastal lagoons in Cape Krusenstern National Monument (CAKR). Coastal lagoons are habitat for fish species that are ...
Inhibition of Stuttering from Second Speech Signals: An Evaluation of Temporal and Hierarchical Aspects
(East Carolina University, 2012)
Stuttering is an intermittent and involuntary speech disorder overtly characterized by syllable repetitions, phoneme prolongations and postural fixations that disrupt the natural flow of speech. Overt stuttering is reduced ...
Inclusion of Knowledge Communities in Planning Processes : An Analysis of Green Infrastructure Planning in Maryland, USA.
(East Carolina University, 2012)
Throughout the United States many natural areas are facing tremendous threats due to increases in population and haphazard development patterns. Recently, green infrastructure planning initiatives have emerged, providing ...
COMMUNITY FLOOD HAZARD MITIGATION AND THE COMMUNITY RATING SYSTEM OF NATIONAL FLOOD INSURANCE PROGRAM
(East Carolina University, 2012)
Flooding events, including coastal, estuarine, and riverine floods, cause considerable losses to individuals and businesses in the United States. In recent decades, over 80 percent of disaster losses nationwide have been ...
Resolving the Role of POU1F1 in Human Growth Hormone Locus Activation
(East Carolina University, 2012)
The human growth hormone gene ( hGH-N) is regulated by a distal locus control region (LCR) composed of five deoxyribonuclease I hypersensitive sites (HSs). The region encompassing HSI and HSII contains the predominant ...
Biopsychosocial Health of Military Members and their Spouses
(East Carolina University, 2012)
Military members and their spouses experience unique stressors compared to civilian couples, making them vulnerable for physical, psychological, and relational health concerns. A systematic literature search, exhaustive ...
Effects of Exogenous and Autocrine Growth Hormone (hGH) on Prostate Cancer Cell Function
(East Carolina University, 2012)
Human growth hormone (hGH) is a major product of the anterior pituitary. In addition to its endocrine activities, hGH overexpression in extra-pituitary tissues has been correlated with the oncogenic behavior of these ...
The Shared Experience of Personalized Spiritual Care Services Between Hospital Chaplains and Hospital-based Healthcare Providers
(East Carolina University, 2012)
The research highlighted in this dissertation offers contributions to both the implementation of and literature related to the biopsychosocial-spiritual (BPS-S) approach to healthcare, in particular as it relates to the ...