Search
Now showing items 31-40 of 54
The role of cardiac mitochondria in myocardial ischemia/reperfusion injury
(East Carolina University, 2012)
Cardiovascular disease (CVD) exerts economic and humanitarian costs that are unparalleled by any other disease. Of the many etiologies of CVD, myocardial infarction accounts for over 50% of the associated mortality and ...
Mathematical Modeling of Oxygen Transport, Cell Killing and Cell Decision Making in Photodynamic Therapy of Cancer
(East Carolina University, 2012)
In this study we present a model of in vitro cell killing through type II Photodynamic Therapy (PDT) for simulation of the molecular interactions leading to cell death in time domain in the presence of oxygen transport ...
PLANNING AND IMPLEMENTING A GLOBAL CURRICULUM : A CASE STUDY OF ONE NORTH CAROLINA ELEMENTARY SCHOOL
(East Carolina University, 2012)
Today the world is more interconnected than ever (Stewart, 2012). Students in the 21st century need competent teachers who use technology as a routine way of learning, and who coach student learning that is authentic and ...
Apigenin prevents chemically-induced skin tumor formation and inhibits COX-2 expression and activity in SKH-1 mouse epidermis
(East Carolina University, 2012)
The most common type of cancer in the United States is non-melanoma skin cancer (NMSC), with an estimated two million new cases diagnosed each year. Numerous malignancies including NMSC, colon, breast, and prostate cancer ...
The Rhetorical Construction of Legal Culture : Ideographs and Relationships in Appellate Opinions Addressing Same-Sex Marriage and English-Only Legislation
(East Carolina University, 2012)
In my dissertation, I present a critical method that presents a framework for both a legal and rhetorical analysis of appellate opinions. The legal analysis will be a traditional form of legal analysis of an opinion, ...
The significance of mirna pathway in peripheral nerve regeneration following sciatic nerve injury.
(East Carolina University, 2012)
microRNAs (miRNAs) are small (21-23 nucleotides) single-stranded RNAs that play important roles in post-transcriptional regulation of gene expression. The binding of miRNA to its specific target mRNAs at 3' UTR causes ...
DETECTION AND DISTRIBUTION OF THE AMPHIBIAN FUNGAL DISEASE CHYTRIDIOMYCOSIS IN PERUVIAN AMPHIBIANS
(East Carolina University, 2012)
Chytridiomycosis is an amphibian disease caused by the fungal pathogen Batrachochytrium dendrobatidis (Bd;Longcore et al. 1999). This disease has been identified by the Amphibian Conservation Action Plan as one of the main ...
SKELETAL MUSCLE METABOLIC FLEXIBILITY IMPAIRMENTS IN RESPONSE TO LIPID WITH OBESITY : EFFECT OF EXERCISE TRAINING
(East Carolina University, 2012)
Obese individuals exhibit skeletal muscle metabolic inflexibility by failing to increase fat oxidation and genes linked with mitochondrial biogenesis in response to a high-fat diet (HFD) and lipid incubation in cell culture. ...
The Region Specific Influence of Estradiol on In-Vivo Lipolysis in Subcutaneous Adipose Tissue in Overweight-to-Moderately-Obese Premenopausal Women
(East Carolina University, 2012)
Premenopausal women demonstrate preferential accumulation of adiposity in the gynoid region, a distribution which shifts towards the abdominal region after the menopausal transition. Although estrogen is implicated as a ...
PARTNERSHIPS AMONG SCHOOLS AND FAITH-BASED ORGANIZATIONS : IMPACT ON STUDENT SUCCESS
(East Carolina University, 2012)
The purpose of this study was to explore the perceived effect of faith-based mentorship on student academic and behavioral success by examining the impact of a specific partnership--the Uplift Mentor Program--a faith-based ...