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Development of Computational Tools and Resources for Cotton microRNA Analysis
(East Carolina University, 2014)
MicroRNAs (miRNAs) are an extensive class of small regulatory RNAs which regulate gene expression at the posttranscriptional levels. miRNAs target genes for mRNA cleavage or translation inhibition based on the complementary ...
RNA polymerase II CTD Evolutionary Diversity and Associated Protein Identification in Green and Red Algae
(East Carolina University, 2014)
In model eukaryotes, the C-terminal domain (CTD) of the largest subunit (RPB1) of DNA-dependent RNA polymerase II is composed of tandemly repeated heptads with the consensus sequence YSPTSPS. Both the core motif and tandem ...
Negative sexual experiences and rape: understanding the relationship between adult and childhood sexual victimization and somatic complaints, psychological factors, and self-rated health in college women
(East Carolina University, 2014)
Sexual Victimization is a major issue in our society. The results of sexual victimization can persist throughout life and can be debilitating. Sexual victimization affects mental, sexual, and physical health. College women ...
A PHENOMENOLOGICAL STUDY OF FIVE HBCU CHANCELLORS IN ONE SOUTHEASTERN STATE
(East Carolina University, 2014)
Founded out of necessity due to overt racism that kept Blacks out of higher education, HBCUs today find themselves in precarious positions to stay relevant in an academic field where PWIs compete for Black students. There ...
Understanding Trauma Reactions in Implantable Cardioverter Defibrillator Patients and Piloting a Brief Web-based Trauma Intervention Protocol Study (ICD-TIPS)
(East Carolina University, 2014)
Background: Approximately 20% of patients with an implantable cardioverter defibrillator (ICD), a medical device that prevents sudden cardiac arrest (SCA) and mortality, score above a clinical cutoff on a screening measure ...
Function and regulation of the polysaccharide utilization locus, don, in the gut symbiont bacteroides fragilis
(East Carolina University, 2014)
Bacteroides fragilis is the most common anaerobe isolated from clinical infections and in this report we demonstrate a novel feature of the species that is critical to their success as an opportunistic pathogen. Among the ...
The involvement of cap-independent mRNA translation in cell fate decisions
(East Carolina University, 2014)
During cell stress many biochemical processes are shut down. For
example, global mRNA translation initiation is inhibited due to the
disruption of the cap-dependent mRNA recruitment mechanism. One
specific example of ...
ADULT ATTACHMENT THEORY AND DIABETES MELLITUS : AN EXAMINATION OF HEALTHCARE UTILIZATION AND BIOPSYCHOSOCIAL HEALTH
(East Carolina University, 2014)
Diabetes mellitus (DM) impacts hundreds of millions of individuals and their families around the globe. To explore the relational aspects of care and healthcare utilization two research articles were written: (a) a systematic ...
The iron response regulator Irr controls iron homoeostasis in Brucella
(East Carolina University, 2014)
Members of the genus Brucella are small, Gram-negative intracellular bacterial pathogens that are capable of infecting a wide range of mammalian hosts including humans. Brucella primarily reside inside of host macrophages. ...
Trauma, Coping, & the Couple Relationship : An Investigation of Pregnant Couples' Biopsychosocial-Spiritual Health
(East Carolina University, 2014)
Pregnancy and trauma are each complex biopsychosocial-spiritual processes with implications for the couple relationship, but there is not enough research on the ways that the two constructs are connected. Two articles were ...