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Antigen-specific tolerogenic vaccines inhibit autoimmune disease in a rodent model of multiple sclerosis
(East Carolina University, 2010)
Multiple sclerosis (MS) is considered to be a T cell-mediated autoimmune disease directed against myelinated nerves within the central nervous system. Current therapies available to MS patients have low efficacy and are ...
Development of a Diffraction Imaging Flow Cytometer for Study of Biological Cells
(East Carolina University, 2010)
Visible light interacts with biological cells primarily through elastic scattering. With coherent excitation the scattered light is coherent as well and contains much information about the cells morphology but with the ...
Enforced expression of HoxA9 in b-lineage all promotes survival and proliferation of leukemic cells
(East Carolina University, 2009)
HoxA9 is frequently overexpressed in acute myeloid leukemia, myelodysplastic syndrome and a subset of acute lymphoblastic leukemia. In mouse models, HoxA9 has been shown to promote leukemogenesis. In spite of a seemingly ...
Appraisal of uncertainty while waiting for a kidney transplant
(East Carolina University, 2012)
This study tested a middle range nursing theory to better understand the experience of uncertainty in deceased-donor kidney transplant candidates with a goal of identifying ways to improve the care of persons by nurses as ...
Investigations into the roles of bacteroides fragilis thioredoxins during the oxidative stress response
(East Carolina University, 2011)
The Gram-negative Bacteroides fragilis is the most frequently isolated bacterium from anaerobic infections. Native to the human intestinal tract, it serves a symbiotic role breaking down complex polysaccharides and ...
A STUDY OF THE EFFECT OF KINDERGARTEN ENTRANCE AGE ON THE REFERRAL AND PLACEMENT RATE INTO THE EXCEPTIONAL CHILDREN'S PROGRAM
(East Carolina University, 2012)
This study examined relationships between specific data on students referred for and placed in the exceptional children's program. The context is a rural North Carolina county and included 206 records of K - 6th graders ...
A COMPARATIVE ANALYSIS OF THE ACADEMIC ACHIEVEMENT OF BAND AND NON-BAND PARTICIPANTS IN CRAVEN COUNTY, NORTH CAROLINA
(East Carolina University, 2013)
This study was intended to compare the academic achievement of students who participated in high school band classes with non-band participants. A problem of practice study was designed to provide data for principals who ...
Ion Traffic Across Cellular Membranes
(East Carolina University, 2010)
The cell membrane protects the delicate internal machinery of the cell and hosts a complex transport system for ion exchange with the environment. Energy is continually expended to maintain a transmembrane electrical ...
Nursing students' nonverbal reactions to malodor in wound care simulation
(East Carolina University, 2012)
Background: wound care is an essential competency which nursing students are expected to acquire. To foster students' competency, nurse educators use high fidelity simulation to expose nursing students to various wound ...
Analysis of Circular Dichroism and Linear Dichroism Spectroscopy
(East Carolina University, 2012)
Circular Dichroism (CD) and Linear Dichroism (LD) spectroscopies measure the difference in absorption between left and right circularly polarized light and parallel and perpendicular linearly polarized light as a function ...