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Interaction of memantine with ethanol consumption and dopaminergic function in high ethanol preferring rats
(East Carolina University, 2009)
N-methyl-D-aspartate (NMDA) receptor antagonists have been reported to decrease ethanol consumption in rodents, but these drugs often produce adverse side effects. Memantine is a neuroprotective and low-affinity, ...
The role of cardiac mitochondria in myocardial ischemia/reperfusion injury
(East Carolina University, 2012)
Cardiovascular disease (CVD) exerts economic and humanitarian costs that are unparalleled by any other disease. Of the many etiologies of CVD, myocardial infarction accounts for over 50% of the associated mortality and ...
PREDICTING TREATMENT ADHERENCE FROM ELECTROPHYSIOLOGICAL BIOMARKERS AND INDIVIDUAL DIFFERENCES IN BEHAVORIAL ACTIVATION (BAS) AND BEHAVIORAL INHIBITION (BIS) SYSTEMS
(East Carolina University, 2014)
Obstructive sleep apnea (OSA) is a common chronic sleep disorder with a demanding and complex treatment regimen. Even though continuous positive airway pressure (CPAP) is a highly effective treatment for OSA, approximately ...
Predicting Treatment Success : Assessing Theoretically-Driven Constructs that Impact the Management of Type 2 Diabetes Mellitus Among African American Women in a Novel Peer-Delivered Small Changes Treatment Approach
(East Carolina University, 2014)
Rural African American women have greater prevalence of Type 2 Diabetes Mellitus (T2DM) and poorer treatment outcomes compared to Caucasians. Some research suggests that self-efficacy, subjective norms, and locus of control ...
Mathematical Modeling of Oxygen Transport, Cell Killing and Cell Decision Making in Photodynamic Therapy of Cancer
(East Carolina University, 2012)
In this study we present a model of in vitro cell killing through type II Photodynamic Therapy (PDT) for simulation of the molecular interactions leading to cell death in time domain in the presence of oxygen transport ...
A process evaluation of the use of a training protocol integrating biofeedback and neurofeedback in a counseling setting: consideration of the working alliance and treatment satisfaction
(East Carolina University, 2014)
Often individuals enroll in counseling services during times of distress, seeking help with a variety of situations and conditions. However, many individuals do not complete treatment for a variety of reasons. A possible ...
THE EFFECT OF SCHOOL CULTURE ON STUDENT ACHIEVEMENT
(East Carolina University, 2014)
This study examined school culture as identified through NC teachers' responses to questions regarding school leadership's sustained effort to address teachers' concerns about leadership issues, facilities and resources, ...
Impact of Educational Messages on Patient Acceptance of Male Medical Students in OB-GYN Encounters
(East Carolina University, 2014)
Medical student education in obstetrics and gynecology (OB-GYN) is an essential part of training and involves direct patient care experiences (APGO, 2012a; Harrell et al., 1993). However, for male students difficulties ...
Project MENTOR+ : Mentor-led exercise with cognitive-behavioral therapy to improve perceived competence, reduce social anxiety, and increase physical activity in overweight adolescents.
(East Carolina University, 2014)
Overweight adolescents are at increased risk for peer victimization and avoidance of physical activity, thus perpetuating overweight status and peer victimization. Avenues of intervention include (1) reducing avoidance ...
Identifying the missing piece of suicide prevention : Formative risk assessment
(East Carolina University, 2014)
Suicide is the third leading cause of death among adolescents and young adults (Centers for Disease Control [CDC], 2011). However, no evidence-based suicide prevention programs currently exist that utilize formative ...