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The extracellular processing of aggrecan aggregate and its effect on CD44 mediated internalization of hyaluronan.
(East Carolina University, 2015)
In many cells the hyaluronan receptor CD44 mediates the endocytosis of hyaluronan and its delivery to endosomes / lysosomes. The regulation of this process remains largely unknown. In most extracellular matrices hyaluronan ...
Fishing For The Evolutionary Bases Of Female Ornamentation
(East Carolina University, 2015)
Sexual dimorphism, or phenotypic differentiation of the sexes, is widespread amongst animals. It is understood mainly in the context of sexual selection, i.e. selection on mating success, with such selection typically ...
Rectifying Limitations On Species Delineation In Dusky Salamanders : Lineage Detection Using An Ecoregion-Drainage Sampling Regime
(East Carolina University, 2015)
The dusky salamanders (Desmognathus) constitute a large, species-rich group, and although a considerable body of literature exists on systematic relationships and adaptive trends, these issues have heretofore been approached ...
Evaluating The Essential Functions Of The Replication Factor Mcm10 In Drosophila Melanogaster
(East Carolina University, 2015)
Often referred to as miraculous, life as we know depends not upon miracles but on a series of highly orchestrated and regulated biochemical processes collectively known as the cell cycle. It is through these series of ...