Browsing Master's Theses by Author "McCubrey, James A."
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The Role of GSK-3[beta] in MCF-7 Breast Cancer Cell Signaling and Drug Resistance
Sokolosky, Melissa Lynn (East Carolina University, 2011)Glycogen synthase kinase- 3beta (GSK-3beta) is well documented to participate in a complex array of critical cellular processes. This versatile protein is involved in numerous signaling pathways that influence metabolism, ... -
Targeting aberrant signaling in the EGFR1/HER2/PI3K/PTEN/Akt/mTORC1/GSK-3 pathway : Novel therapeutic interventions in breast cancer
Davis, Nicole Marie (East Carolina University, 2015)Breast cancer is attributed to being the second most deadly cancer in American women. Approximately 1 in 8 women will be diagnosed with breast cancer during her lifetime, and prognosis is dependent upon the genetic make-up ... -
The role of the Bcl-2 protein in the drug resistance of human breast cancer cells
Davis, Julianne M. -
The role of the Bcl-2 protein in the drug resistance of human breast cancer cells
Davis, Julianne M.