Browsing Master's Theses by Subject "Biological Phenomena"
Now showing items 1-2 of 2
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A Smad3/FoxO3 Transcriptional Relationship in the Regulation of Vascular Growth
(East Carolina University, 2019-06-05)Cardiovascular disease (CVD) is a multi-faceted pathological condition that continually ranks as the number one cause of morbidity and mortality in the United States and worldwide. Unfortunately, despite extensive basic ... -
Understanding the Molecular Mechanisms that Contribute to Parkinson’s Disease: Defining the Role of Ca2+ in TG2: α-synuclein Macromolecular Complex Assembly
(East Carolina University, 2018-12-10)Transglutaminase 2 (TG2) is an allosteric enzyme ubiquitously expressed in human tissue. This versatile enzyme has both Ca2+ -dependent, transamidase and GTPase activities. TG2's Ca2+ -dependent transamidase activity is ...