Browsing Master's Theses by Subject "Heavy metals"
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Thermodynamic and spectroscopic studies of Cd²⁺ binding to the regulatory domain and full length human cardiac troponin C (HcTnC) : elucidating plausible Cd²⁺ binding sites
(East Carolina University, 2015)Toxic metals such as cadmium (Cd²⁺) have been shown to bind to and interfere with various calcium (Ca²⁺) binding proteins including the regulatory protein cardiac troponin C (cTnC). Recent structural data has shown that ... -
Toxic Metal Interactions with Human Cardiac Troponin C and Cysteine Replacement Mutants: Investigating Potential Cd(II) Binding to Cysteine Thiols Using DTNB Time Course Assays
(East Carolina University, 2021-07-26)Calcium binding proteins contribute to all aspects of cell function by binding to calcium directly. Human Cardiac Troponin C (hcTnC) belongs to the EF-hand family of calcium binding proteins. This specific protein is ...