Browsing Master's Theses by Subject "Medicine"
Now showing items 1-9 of 9
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Applications of Stochastic Processes to Cancer Research
(East Carolina University, 2013)The purpose of this thesis is to implement stochastic models that are currently used to analyze the impact of different drug treatments on cancer and to model drug resistance by cancer cells. Mathematical models are used ... -
Cardiac and Mitochondrial Adaptations in Response to Aging and Doxorubicin in Rats Bred for Divergent Aerobic Capacities
(East Carolina University, 2012)Doxorubicin (DOX) remains as one of the most widely prescribed and effective anticancer agents. A major limitation of the therapeutic effectiveness of the drug is the occurrence of irreversible, progressive, dose-dependent ... -
General And Device-Specific Quality Of Life In Arrhythmogenic Right Ventricular Cardiomyopathy Patients : The Impact Of Shock And Sex
(East Carolina University, 2015)Background: Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a heritable cardiac condition that weakens the heart and results in frequent and often life-threatening arrhythmias, requiring the placement of an ... -
Genetic control of cell fate specification in Caenorhabditis elegans germline.
(East Carolina University, 2015)The precise regulation of germ cell fates (sperm or oocyte) lies at the heart of reproduction and fertility. The nematode Caenorhabditis elegans hermaphrodites produce a discrete number of sperm during larval development ... -
Hypoxia and Serum Deprivation in Human Mesenchymal Stem Cells, and the Protective Role of Thymosin [Beta]-4
(East Carolina University, 2011)Background: Current literature suggests nutrient deprivation and hypoxia affect human mesenchymal stem cell (hMSC) survival after cell transplantation. Wound-healing protein Thymosin [beta]-4 (T[beta]-4) has been shown ... -
Integrative Health Coaching : A Phenomenology of Clients' Discoveries
(East Carolina University, 2012)The field of health coaching has experienced significant growth in response to the social and economic burden of chronic disease. Integrative health coaching (IHC) applies the principles of integrative medicine and a ... -
miRDiabetes : A microRNA-Diabetes Association Database Constructed With Data Mining on Literature
(East Carolina University, 2014)MicroRNAs (miRNAs) are a growing class of non-coding RNAs that regulate gene expression by translational repression. A role for miRNA in diabetes was first established in 2004 and research in miRNA-diabetes association has ... -
Pediatric Behavioral Concerns : Does Physician Training Influence Their Referral and Recommendation Practices
(East Carolina University, 2014)Pediatric primary care physicians indicate behavioral health concerns to be the most frequently reported complaint of parents during well-child visits. Over the last few decades, graduate medical education and training ... -
The Health and Medical Care of Enslaved African Americans at Somerset Place, 1839-1863
(East Carolina University, 2018-07-24)Somerset Place was one of the largest plantations in North Carolina at the end of the Antebellum period. The owner of Somerset Place, Josiah Collins III, owned the third largest slave plantation in the state. Slaves at ...