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AMP Deaminase 3 knockout mice and loss of mitochondrial proteins and enzyme activity during denervation atrophy
(East Carolina University, 2018-07-17)
Muscle atrophy leads to decrements in muscle function, partly attributable to decreased mitochondrial content. One controller of mitochondrial content is AMP-activated protein kinase (AMPK), which when bound by AMP activates ...
Understanding Wearable Cardioverter Defibrillator Use and Activity Level in Pediatric Populations
(East Carolina University, 2018-07-20)
Research suggests that most patients utilize WCDs appropriately. However, very little is known about pediatric cardiac patients prescribed a wearable cardioverter defibrillator (WCD). In other pediatric cardiac populations, ...
Prisons and Pollutant Plumes: A Spatial Analysis of LULU Coexistence
(East Carolina University, 2018-07-20)
Prison facilities and other locally unwanted land uses (LULUs) lead to a number of health, environmental, and socio-economic impacts on the local community. Prison facilities and other LULUs tend to be sited in locations ...
Counting Protons: Using Isothermal Titration Calorimetry to Determine the Number of Protons Exchanged Upon Ca(II) and Cd(II) Binding to Wild-type HcTnC and Mutant C84A and C35A/C84A Proteins
(East Carolina University, 2018-07-20)
Maintaining a delicate balance of metal ions in the cell is crucial to the survival of many organisms. Divalent cadmium, Cd(II), is a non-essential metal ion that can disrupt this delicate balance and lead to deleterious ...
Motion-Based Segmentation of Medical MRI Images: A Review and Analysis
(East Carolina University, 2018-07-20)
Image data produced in medical field assists doctors, surgeons and researchers to study muscle and tissue structure to identify and diagnose patient specific diseases and deficiency. Due to the complexity of muscle ...
Geometry and Progressive Development of a Shallow Crustal Intrusive Complex, Mount Hillers, Henry Mountains, Utah
(East Carolina University, 2014)
The Henry Mountains of southeastern Utah are five topographic domes, each of which is a separate mid-Tertiary shallow crustal intrusive complex comprised of a cluster of component igneous intrusions. The intrusions were ...
The Relationship between Gait Biomechanics and Body Mass Index
(East Carolina University, 2014)
Walking gait is one of the basic components of human movements. With the rising obesity epidemic and implied health complications, it is pertinent to examine the relationship between body mass index and the joint torques ...
The Personality Correlates of Driving While Intexticated
(East Carolina University, 2012)
The present study attempted to identify the antecedents of texting while driving. Specifically, this study looks at the relationship between personality traits (i.e., the Big-Five), trait risk taking, and the cognitive ...
THE EFFECTS OF CIRCADIAN RHYTHM ON INFLAMMATORY RESPONSE AND CYTOKINE LEVELS IN HEPATIC MACROPHAGES
(East Carolina University, 2014)
In mammals, many aspects of daily behavior and physiology such as the sleep-wake cycle, body temperature, and liver metabolism are regulated by endogenous circadian mechanisms. Despite tissue-specific physiological ...
Effects of Alternative Seating on the Academic Engagement of Children With Autism
(East Carolina University, 2010)
Students with sensory integration deficits may display a hyper or hyposensitivity to sensory information and lack the ability to modulate that input in socially appropriate ways. Therapy balls as a sensory integration ...