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A single dose of metformin improves whole body insulin sensitivity and alters cellular redox state in skeletal muscle of Zucker fa/fa rats
(East Carolina University, 2010)
Energy balance is considered a fundamental requirement of life forms from single cell organisms to higher mammals such as humans. Unfortunately, our species has also discovered the detrimental metabolic responses to excess ...
Intron position in RNA polymerase genes and their relationship to eukaryotic phylogenies
(East Carolina University, 2010)
Over the past two decades, there has been an increasing amount of research devoted to the study of intron evolution and its relationship to eukaryotic phylogeny. Previous studies have shown that a large percentage of ...
STRIDE LENGTH MANIPULATION IN YOUNG AND OLD ADULTS DURING LEVEL WALKING
(East Carolina University, 2010)
Physiological and neurological changes with healthy aging cause old adults to alter biomechanical gait strategies. Mechanical plasticity is an ambulatory strategy in which old adults rely on proximal musculature in ...
Psf2, a member of the heterotetrameric GINS Complex, plays a role in cell cycle progression and maintenance of genomic integrity
(East Carolina University, 2010)
Multiple proteins are involved in the complete and accurate replication of the genome during S phase of the cell cycle. At the G1/S phase transition, the heterotetrameric GINS complex is recruited to the origin, and ...
Coyotes Sang the Braid Into Her Hair
(East Carolina University, 2010)
A chapbook length collection of lyric poetry that explores the myth-making process through the tension of opposites: the nature of the substantive (body) and the ephemeral (mind), the wild vs. the tame self, the rational ...
Can Passive Acoustics be Used to Estimate the Length of Atlantic Croaker (Micropogonias undulatus) within the Pamlico Estuary?
(East Carolina University, 2010)
The Atlantic States Marine Fisheries Council (AFMFC) attributes the decline in the Atlantic croaker (Micropogonias undulatus) stock to over-fishing practices. The majority of collected Atlantic croaker are small, young of ...
Obese Children Have a Lower Lipolytic Response to an Acute Bout of Exercise When Compared to Lean
(East Carolina University, 2010)
Over 17% of American children are obese. These are epidemic proportions considering the associated risk of heart disease and Type 2 diabetes. Excess fat is caused from an imbalance in energy stored versus energy expended. ...
LOCALIZATION AND CHANGES OF NUCLEAR PROGESTERONE RECEPTORS IN ZEBRAFISH OOCYTES AND ADJACENT FOLLICULAR CELLS
(East Carolina University, 2010)
The nuclear progesterone receptor (Pgr) is one of the major mediators for progestin signaling during oocyte ovulation in vertebrates. However, any roles Pgr may play in oocyte growth, and especially in the final oocyte ...
Interaction and Functional Analysis of Drosophila Mcm10
(East Carolina University, 2010)
In eukaryotic cells, DNA replication and the subsequent packaging of DNA into specific chromatin states are essential processes for the transmission of genetic material and genomic stability which may be linked by interactions ...
Effect of green tea Polyphenon 60 on microRNA expression in MCF-7 breast cancer cells
(East Carolina University, 2010)
In Western countries, breast cancer is the most common form of cancer and it is the second leading cause of female cancer death in America. The biochemical basis of the observed anti-oncogenic properties of green tea has ...