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Photofrin-Mediated Electroporation-Assisted Photodynamic Therapy of MCF-7 Human Breast Cancer and B16-F10 Mouse Melanoma Cells
(East Carolina University, 2011)
Photodynamic therapy is a relatively new player on the field of cancer treatment that involves the injection of a nontoxic light-sensitive drug followed by light excitation, creating reactive oxygen species that cause ...
Role of Notch signaling in tumorigenesis, stemness, and epithelial to mesenchymal transtion in colorectal cancer.
(East Carolina University, 2015)
Colorectal cancer is the third most commonly diagnosed cancer in both men and women in the United States. Surgical resection and combination chemotherapy are often used for treatment, but in later stages of the disease, ...
Comparison of ZnO nanoparticles and ZnCl₂ induced germ cell apoptosis in Caenorhabditis elegans
(East Carolina University, 2014)
There is inadequate research data available on manufactured ZnO nanoparticles. Manufactured nanoparticles are widely used in various products and production of manufactured nanoparticles is becoming increasingly abundant. ...
miRDiabetes : A microRNA-Diabetes Association Database Constructed With Data Mining on Literature
(East Carolina University, 2014)
MicroRNAs (miRNAs) are a growing class of non-coding RNAs that regulate gene expression by translational repression. A role for miRNA in diabetes was first established in 2004 and research in miRNA-diabetes association has ...
Evaluating Land Use Effects On The Stinging Sea Nettle : Chrysaora Quinquecirrha: Are Shoreline Hardening Structures Creating New Habitat For A Nuisance Species?
(East Carolina University, 2015)
There is considerable debate as to whether global jellyfish populations are experiencing an overall population growth due to human activities or have been pulsing in a long-term natural rhythm. Empirical data to support ...
Population Structure Of River Herring In Albemarle Sound, North Carolina, Inferred From Geometric Morphometrics And Otolith Shape Analysis
(East Carolina University, 2015)
Alewife Alosa pseudoharengus and Blueback Herring Alosa aestivalis, collectively known as River herring, use tributaries of the Albemarle Sound, North Carolina as spawning and nursery habitats. Stocks of these anadromous ...
Assessing The Monophyly Of Red Algae And Green Plants Via Core Conserved Informational Genes
(East Carolina University, 2015)
For well over a century the existence of a monophyletic relationship between red algae and green plants has been debated. Many scholars have sought to address this issue, however, a consistent solution to the problem has ...
Metabolic, Physiological, And Behavioral Responses Of Prey To Predation
(East Carolina University, 2015)
Predators are known to cause prey to alter their morphology, life history or behavior in ways that reduce the likelihood of the prey being consumed by the predator. Seldom considered, however, are the consequences of ...
Possible Effects Of Climate Change On Induced Defenses In Tadpoles
(East Carolina University, 2015)
Global climates are changing and the rate of change is expected to increase in the next century. Researchers predict that temporary ponds will be affected, resulting in shorter average hydroperiods (the amount of time a ...
Neurological Effects Of A Single Low Level Blast Overpressure Exposure : Behavior And Micro RNA Mechanisms Of Mild Traumatic Brain Injury In A Rodent Model
(East Carolina University, 2015)
The increased use of explosive devices within warfare and acts of terrorism has allowed blast overpressure exposure (BOE) to become a significant concern. The most common wound sustained by BOE is blast-induced mild traumatic ...