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NADPH Oxidase as a Mechanistic Link Between Erectile Dysfunction, Peripheral, and Coronary Endothelial Dysfunction in Obesity
(East Carolina University, 2012)
Cardiovascular complications involving both microvascular and macrovascular tissues are the major cause of morbidity and mortality in obese patients. Clinical and epidemiological studies suggest that erectile dysfunction ...
SELF-DETERMINATION THEORY AND MOVEMENT TECHNOLOGY IN COLLEGE PHYSICAL ACTIVITY CLASSES
(East Carolina University, 2014)
The college-age population is not sufficiently physically active and physical activity declines markedly during the college years. Interventions in university and college settings are potential avenues for increasing ...
The Influence of Energy Expenditure on Mitochondrial Functions, Oxidative Stress and Insulin Resistance under Metabolic Oversupply Conditions
(East Carolina University, 2011)
Mitochondrial respiratory capacity and oxidative stress have been implicated in the development of insulin resistance (IR) and type II diabetes. A causative role of mitochondrial oxidative stress in the etiology of ...
REGULATION OF LIPOLYSIS BY [BETA]-ADRENERGIC ACTIVATION AND EXERCISE IN OBESE AFRICAN-AMERICAN AND CAUCASIAN WOMEN
(East Carolina University, 2012)
African-American women (AAW) are twice as likely to be obese as Caucasian women (CW); however, previous in-vitro studies have shown that AAW have higher densities of beta-adrenergic receptors (B-AR) in the subcutaneous ...
EFFECTS OF A 16 WEEK PHYSICAL ACTIVITY INTERVENTION ON SERUM C-REACTIVE PROTEIN CONCENTRATIONS IN 8-11 YEAR OLD AFRICAN AMERICAN AND CAUCASIAN CHILDREN.
(East Carolina University, 2013)
C-reactive protein (CRP) is a non-specific marker of systemic inflammation that has been associated with heart disease, obesity, and metabolic disorders in adults and children. Previous physical activity interventions have ...
ASSOCIATION OF PARK-USE, PREFERENCES OF PARK FEATURES, AND PHYSICAL ACTIVITY AMONG CITY RESIDENTS VARYING IN SOCIOECONOMIC STATUS
(East Carolina University, 2014)
Public parks can play a substantial role in increasing physical activity (PA) because they offer a wide range of either free or low-cost activities. For many Americans, there are limitations on the environment and resources ...
IL-15 : A NOVEL REGULATOR OF LIPOLYSIS IN HUMANS?
(East Carolina University, 2014)
Interactions between and within organ systems such as skeletal muscle (SkM) and adipose tissue (AT), via immune cell signaling factors (cytokines), may regulate the development of obesity. The increased expression and ...
VARIABILITY IN POPLITEAL ARTERY BLOOD FLOW : EFFECT OF EXERCISE TRAINING
(East Carolina University, 2012)
Mean arterial pressure (MAP) is regulated through changes in cardiac output (Q) and total peripheral resistance (TPR), where Q = heart rate (HR) x stroke volume (SV). Healthy heart rhythms have inherent variability and a ...
SKELETAL MUSCLE METABOLIC FLEXIBILITY IMPAIRMENTS IN RESPONSE TO LIPID WITH OBESITY : EFFECT OF EXERCISE TRAINING
(East Carolina University, 2012)
Obese individuals exhibit skeletal muscle metabolic inflexibility by failing to increase fat oxidation and genes linked with mitochondrial biogenesis in response to a high-fat diet (HFD) and lipid incubation in cell culture. ...
Introducing portable pedal machines inside a university library to reduce sedentary behavior
(East Carolina University, 2013)
Background: Sedentary behavior is a health risk factor independent of time spent in moderate-to-vigorous physical activity. Sedentary behavior takes place frequently in libraries. Few sedentary behavior interventions ...