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Social and Environmental Factors Associated with Preschoolers' Non-sedentary Physical Activity
(East Carolina University, 2009-01)
The two-fold purpose of the investigation was (1) to describe with direct observation data the physical
activity behaviors and the accompanying social and environmental events of those behaviors for children in preschools; ...
Deletion of the Protein Kinase A/Protein Kinase G Target SMTNL1 Promotes an Exercise-adapted Phenotype in Vascular Smooth Muscle
(East Carolina University, 2008-04-25)
In vivo protein kinases A and G (PKA and PKG) coordinately phosphorylate a broad range of substrates to mediate their various physiological effects. The functions of many of these substrates have yet to be defined genetically. ...
Factors Related to Objectively Measured Physical Activity in Preschool Children
(East Carolina University, 2009-05)
This study examined correlates of objectively measured physical activity (PA) in a diverse sample of preschool children (age 3–5 years; n=331). Accelerometer min·hr−1 of moderate-to-vigorous physical activity (MVPA) and ...
Metabolic Inflexibility in Skeletal Muscle With Obesity
(East Carolina University, 2009)
The skeletal muscle of obese individuals has a reduced capacity to oxidize lipids. The hypothesis to be tested in this dissertation is that the ability to regulate lipid oxidation in response to lipid exposure is impaired ...
Insights into the Evolution of Environmental Health
(2009-03-13)
Muscle Work Discrepancy during Incline and Decline Running at Three Speeds
(East Carolina University, 2009)
Introduction: Previous research has explored muscle function during gait and this work has shown that more positive mechanical muscle work is produced in gait tasks that primarily raise the center of mass (incline gait ...
Gender Differences in Aerobic and Work Capacity During Plantar Flexion Exercise
(East Carolina University, 2009)
Maximal oxygen consumption (VO2max) is lower in females compared to males during traditional whole body, systemic exercise. These differences in VO2max between men and women are still present even after correcting for ...
Effect of Acute Exercise or Fasting on Mitochondrial Function and High Fat Diet-Induced Insulin Resistance
(East Carolina University, 2009)
A high-fat diet leads to an accumulation of lipid in skeletal muscle, and the development of both mitochondrial dysfunction and insulin resistance. Recently, our lab reported that lipid overload leads to elevated ...
Muscles do more positive than negative work in human locomotion
(East Carolina University, 2007-10)
Muscle work during level walking and ascent and descent ramp and stairway walking was assessed in order to explore the proposition that muscles perform more positive than negative work during these locomotion tasks. Thirty ...
How do low horizontal forces produce disproportionately high torques in human locomotion?
(East Carolina University, 2008)
Although horizontal ground forces are only ~15% of vertical forces, they account for 47% and 33% of the metabolic cost in walking and running. To explain these disproportionately high metabolic costs we hypothesized that ...